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Progesterone lozenge and anxiety

by Katie Ball
(Oxford, England )

So I have been recommended progesterone lozenges by a hormone specialist. I didn’t have blood tests as I was on the contraceptive pill but all my symptoms after childbirth a year ago pointed to low progesterone.

I was also prescribed metaformin for PCOS which I’ve been taking over a week with no side effects. I took the first lozenge 2 nights ago. They are 150mg and was told to take 1/4 of a tablet, well yesterday and all through last night all my symptoms heightened, sweats, anxiety, headache, no appetite! I was too scared to take another 37.5mg lozenge last night and now I can slowly feel the anxiety wearing off!

I don’t know what to do or why this happened! Does this prove that I am low in progesterone and I just need more? Or does this mean that low progesterone isn’t my problem and that’s why I got the side effects of anxiety?

Any experienced advice would be really appreciated

Comments for Progesterone lozenge and anxiety

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Jan 08, 2021
 Progesterone lozenge and anxiety
by: Joy

Hi Katie

Oral progesterone is not the best Delivery Method as around 96% gets destroyed by the gut and liver. Please consider using and good organic progesterone cream such as Natpro. The amount that you are taking will merely aggravate estrogen receptors which is causing your adverse symptoms. Between 100-200mg progesterone cream is needed per day. Use half the amount in the morning and the other half at night, never use progesterone once a day as this causes progesterone levels to spike. Once your symptoms clear and you feel stable enough you can use the cream by following your cycle, i.e. your luteal phase. The How to use Progesterone Cream page explains this in far more detail.

The contraceptive pill causes so many problems, they have a potential to cause harm, see here. They also keep you in a permanent state of Estrogen Dominance. The aim of progesterone therapy is to make progesterone the dominant hormone at all times.

You might also like to read the Anxiety and PCOS pages. I do hope that your doctor prescribed vitamin B12 when taking metformin as it destroys B12, see here.
Jan 08, 2021
 Anxiety
by: Katie

Thank you so much for your response I’m really grateful.
Basically I had a baby august 2019 and 6 months after having my baby suddenly started experiencing panic and anxiety I have never suffered any mental health issues so this really scared me, I’ve spent the last 8 months on antidepressants because that is all the doctor would suggest and I still don’t feel quite right, although the antidepressants masked the really strong anxiety I feel like that is all it is doing is masking the problem and then I went to see a hormone epacialist who said I probably have low progesterone but didn’t do a blood test as I was on the CP. When I took that one quarter of a lozenge the anxiety all came back so it’s put me right off!

I really just want to feel like myself again! The doctor looked at my bloods done by my gp and said I probably have PCOS so put me on Metformin which I haven’t had any issues with and is helping my acne from what I can tell.

Have u ever dealt with anyone in my situation before and the lozenge didn’t work but the cream did? I had blood tests done for b12 and vit d and folate 6 months ago and I was low but the tablets aggregate my anxiety! I don’t know why?!
Jan 12, 2021
 Progesterone lozenge and anxiety
by: Joy

Hi Katie

The quarter lozenge that you took would cause anxiety. As mentioned when not enough progesterone is used it affects estrogen receptors. A good progesterone cream is an excellent option as mentioned.

I can't understand who you doctor could say that you "probably have PCOS", either you do or you don't.

Many experience what you are going through. If progesterone is used correctly it will help. I explained to you why the lozenge or any oral progesterone is not the best delivery method.

You could also be suffering from PND after the birth of your baby. PND, panic attacks, anxiety etc, 400-500mg/day or more is needed. Dr Dalton used levels of 400mg, 800mg, and up to 2400mg/day for her patients with post natal psychosis, see here.

I do hope that you have read the pages given to you.

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