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Natpro Tube Information


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Description of Contents

Natpro is an aqueous cream made exclusively of vegetable based ingredients. It is soy free, GMO free, paraben free and gluten free.

It is supplied in tubes, each of which contains 60 grams (2 oz) of cream. Natpro has a concentration of 3.33% or 33.33 milligrams per gram. 5ml (1 level teaspoon) of cream gives you 166mg of progesterone. Each tube is sufficient for one cycle length or 20 days depending on your required dosage. Although Natpro is supplied in single tubes research has established that for the majority of people the full benefits may only be realised after 3 months use. Please bear this in mind when using and purchasing.

Each tube of Natpro contains :

•De-ionised water
•Caprylic/capric triglyceride
•Progesterone Ph. Eur. USP. JP.
•Sodium olivoil glutamate
•Populus tremuloides
•Xanthan Gum (and) Lecithin (and) Sclerotium Gum (and) Pullulan
•Vitamin E (d-alpha tocopherol)
•Nicotinamide’ (vitamin B3)

*Ecocert approval for use in natural and organic skin care.

Ingredients in detail...

•De-ionized Water - this is an industry standard for water purification.

•Caprylic/Capric Triglycerides - is a medium chain triglyceride of fractionated vegetable fatty acids extracted from coconuts. It is colourless, neutral in odour and taste, and has a very low viscosity. It has very good resistance to oxidation. It serves as a carrier and transport vehicle for active ingredients, as it penetrates the skin readily, being easily absorbed. It does not leave a greasy film and helps to retain moisture.

•Progesterone Ph. Eur. USP JP - Is derived principally from stigmasterol, a steroidal sapogenin. Phytosterols are chemically similar to cholesterol which is found in animals. Cholesterol is the starting point for the hormones made naturally in animals, including humans. Plants such as the soy bean, Dioscorea species of yams, fenugreek, sisal, calabar bean, some lilies, yucca, some solanum species, maize and many more contain phytosterols, some of which are stigmasterol, diosgenin, sitosterol, campesterol, hecogenin, smilagenin, sarsasapogenin, solasodine. As these sterols have a similar molecular structure to progesterone, they are used as starting points for the synthesis of progesterone. The progesterone used in Natpro is synthesised from the wild yam.

•Sodium Olivoil Glutamate - Sodium OLIVOIL Glutamate is a non-ethoxylated, vegetal derived surfactant that combines the unique fatty acid profile of olive oil with the characteristic affinity of glutamic acid toward the skin surface.

The quest for PEG-free emulsifiers led to the creation of new classes of base ingredients, one of which is this skin-friendly and environmentally-friendly Sodium OLIVOIL Glutamate.

This new emulsifier structure provides:

  • high skin compatibility, suitable for sensitive skin as well as babies or children’s skin
  • protecting, soothing and restoring functionality
  • maximum biodegradability according to the CEE regulation N.82/242 OECD Method 

As the whole concept of creating a more efficient equilibrium between ones skin and ones body has increased in popularity, we are seeing an increased success with ingredients of natural origin, embracing the concepts of respect for your skin, or skin friendly emulsifiers.

This is due to 2 main aspects:

  • The need for developing formulas as much as possible compatible with the physiology of skin and its annexes, without any adverse effect or allergic potential.
  • The growing confidence of consumers in the beneficial properties provided by complex mixtures of natural ingredients.

•Populus Tremuloides - a natural preservative made from non GM aspen trees. ‘Aspen bark extract’ as such is a unique discovery, as it is an effective natural replacement for commonly used harmful chemical preservatives. It also improves the emollience (the 'feel good' factor) of the cream.

•Xanthan Gum (and) Lecithin (and) Sclerotium Gum (and) Pullulan - Patented optimised combination of phospholipids and polysaccharides, this is a natural stabiliser gelling agent that leaves an amazing silicone-like skin feel.

It is a preservative-free, ecofriendly, foolproof gelling agent with amazing silicone-like skin feel & texture and 100% natural origin. Also, serves as a thickener, co-emulsifier, stabilizer, suspending agent and skin feel enhancer. This green processed ingredient shows high compatibility with electrolytes.

This senso-active functional ingredient improves active ingredient efficacy and offers skin hydration for true active textures. It provides softness properties demonstrating highly attractive sensory identity. It brings hydration for a 100% active base and reinforces the protective barrier which decreases TEWL and therefore helps keep the skin moisturized.

•D-alpha Tocopherol (Vitamin E) - All emulsions made with vegetable oils have the potential to go rancid. For this reason d-alpha tocopherol is used as it’s an in vitro antioxidant.

•Nicotinamide (Vitamin B3)  -Nicotinamide, also known as niacinamide, is a form of vitamin B3 that offers numerous benefits for skin health.

Key Benefits of Nicotinamide for Skin:

  • Enhances Skin Barrier Function. Nicotinamide helps build keratin, a protein essential for maintaining skin health. It strengthens the skin's lipid barrier, which locks in moisture and protects against environmental irritants, making it beneficial for all skin types, particularly those with conditions like eczema and rosacea.
  • Reduces Inflammation. This ingredient is known for its anti-inflammatory properties, which can help calm redness and irritation associated with acne, rosacea, and other inflammatory skin conditions. By reducing inflammation, nicotinamide can improve overall skin tone and texture.
  • Minimizes Pore Appearance. While it does not physically reduce pore size, nicotinamide can help minimize their appearance by keeping the skin smooth and regulating oil production, which prevents clogged pores and breakouts.
  • Treats Acne. Nicotinamide has been shown to be effective in treating acne vulgaris. Clinical studies indicate that topical nicotinamide gel can be as effective as traditional topical antibiotics in reducing acne lesions. Additionally, it decreases sebum production, which contributes to acne development.
  • Addresses Hyperpigmentation. Research suggests that formulations containing 5% nicotinamide can lighten dark spots and improve skin tone over time. This effect is attributed to increased collagen production and improved skin texture.
  • Protects Against Sun Damage. Nicotinamide enhances the skin's ability to repair DNA damage caused by UV exposure and may reduce the risk of certain types of skin cancer in high-risk individuals. However, it should not be used as a substitute for sunscreen.
  • Reduces Fine Lines and Wrinkles. Topical application of nicotinamide has been linked to improvements in fine lines and wrinkles due to its ability to stimulate collagen production and improve skin elasticity. Studies have reported significant improvements in signs of aging after consistent use over several weeks.
  • Increases Hydration. Nicotinamide helps reduce transepidermal water loss (TEWL), thereby increasing hydration levels in the upper layers of the skin. This makes it particularly beneficial for dry or dehydrated skin types.

Natpro does not contain:
* animal derivatives
* mineral oils
* colorants
* scents
* synthetic antioxidants
* synthetic preservatives
Natpro is not tested on animals.

Natpro has a pH which is in balance with the skin and can be used by anyone with a dietary or environmental concern.

When And How Much Natpro to Use

The cream can be used at any time of the day and, if preferred, on more than one occasion, but no less than twice a day, as progesterone levels drop after about 13 hours. It can be applied to any part of the body and does not have to be used only on the thin skinned areas as is sometimes recommended. The skin comprises 95% kerotinocytes, which have a plentiful supply of progesterone receptors, even the hair follicles absorb it well.
Please note the amount suggested is a guide only as each individual is different. It’s only by trial and error that the correct amount is found. Another point to remember is that stress drops progesterone levels sharply so apply more to prevent the return of symptoms.

Progesterone should always be used dependant on symptoms and not on ‘dose’. If symptoms are severe more will be needed, if mild then less.

Generally between 100-200mg/day of progesterone (that is 3ml to 6ml of cream) is needed.

Women

Menstruating
If a cycle is present apply the cream twice daily from ovulation for the next 14 days, bleeding should occur within a day or two. The luteal phase is always 12-14 days in all women, any less and it’s known as a ‘defective luteal phase’ Cycles vary from 21 days to 36 days. For instance in a 21 day cycle the cream should be used from day 8 for 14 days, if a 28 day cycle from day 15 for 14 days, and if a 36 day cycle from day 22 for 14 days.

Peri or post Menopausal, Hysterectomy, Oophorectomy, Pre-pubertal, Pubertal
If there is no cycle, or an erratic one too difficult to follow, apply the cream twice daily. There is no need for a break as some suggest, although some women prefer to have one. Either is fine.

Severe symptoms:
Hot flushes: Use at least 400mg/day for 4-5 days, this generally stops them. It’s best to apply the cream hourly.

Heavy, continual bleeding: 400-600mg/day from 1 to 3 months, ignoring the cycle. When the bleeding has stopped, slowly reduce the cream until bleeding occurs again, then discontinue the cream for 14 days. Then start again from day 15 for 14 days. Over the coming months the natural cycle length will assert itself. It’s best to apply the cream hourly.

A multitude of bad symptoms: Use a minimum of 200mg/day following the cycle, more might be needed. If symptoms return during the break, then continue applying the cream twice daily or more frequently until they resolve. Once they have then begin following the cycle again.


Men

Use from 10 to 100mg/day of progesterone (that is 0.3ml to 3 ml of cream). It’s best applied twice a day.


For further advice on how to use it please refer to this web page…..

How to use progesterone cream

Supplemental progesterone can initially make a person more sensitive to the oestrogen in their body. Because of this, oestrogen dominance may occur which can be very disconcerting. The following is a short list of what can be encountered …..

  • breast tenderness
  • bloating/weight gain from water retention
  • spotting or a temporary reappearance of your periods
  • headaches/ migraines/ dizziness
  • hypoglycaemia
  • aches and pains or bruising
  • depression
  • tiredness/chronic fatigue
  • hot flushes
  • mood swings
  • anger
  • skin problems
  • nausea

Before using Natpro, it is important to read this page first…. Estrogen Dominance


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