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Dec 19, 2024

Katie

ENDOMETRIAL HYPERPLASIA. Has anyone successfully treated this condition with progesterone cream with lasting effects? I am booked for a hysterectomy so

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Dec 15, 2024

Itchiness and Psoriasis on legs

I'm 46, have used 400mg of natpro daily for many months now (I live in extreme stress due to personal circumstances), and only in the luteal phase for

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Dec 10, 2024

Sodium Olivoil Glutamate

The emulsifier in our new Natpro 60ml tubes remains olive oil based but has been changed from ‘cetearyl olivate/sorbitan olivate’ to ‘sodium olivoil glutamate'.

Sodium Olivoil Glutamate Infographic

Sodium OLIVOIL Glutamate is a non-ethoxylated, vegetal derived surfactant that combines the unique fatty acid profile of olive oil with the characteristic affinity of glutamic acid toward the skin surface.

The quest for PEG-free emulsifiers led to the creation of new classes of base ingredients, one of which is this skin-friendly and environmentally-friendly Sodium OLIVOIL Glutamate.

This new emulsifier structure provides:

•high skin compatibility.•suitable for sensitive skin as well as babies or children’s skin.•protecting, soothing and restoring functionality.•maximum biodegradability according to the CEE regulation N.82/242 OECD Method.

As the whole concept of creating a more efficient equilibrium between ones skin and ones body has increased in popularity, we are seeing an increased success with ingredients of natural origin, embracing the concepts of respect for your skin, or skin friendly emulsifiers.

This is due to 2 main aspects:

1. The need for developing formulas as much as possible compatible with the physiology of skin and its annexes, without any adverse effect or allergic potential.

2.The growing confidence of consumers in the beneficial properties provided by complex mixtures of natural ingredients.

Visit our store at Organic Products.

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Dec 10, 2024

Sodium Olivoil Glutamate

Sodium Olivoil Glutamate Infographic

The emulsifier in our new Natpro 60ml tubes remains olive oil based but has been changed from ‘cetearyl olivate/sorbitan olivate’ to ‘sodium olivoil glutamate'.

Sodium OLIVOIL Glutamate is a non-ethoxylated, vegetal derived surfactant that combines the unique fatty acid profile of olive oil with the characteristic affinity of glutamic acid toward the skin surface.

The quest for PEG-free emulsifiers led to the creation of new classes of base ingredients, one of which is this skin-friendly and environmentally-friendly Sodium OLIVOIL Glutamate.

This new emulsifier structure provides:

•high skin compatibility.•suitable for sensitive skin as well as babies or children’s skin.•protecting, soothing and restoring functionality.•maximum biodegradability according to the CEE regulation N.82/242 OECD Method.

As the whole concept of creating a more efficient equilibrium between ones skin and ones body has increased in popularity, we are seeing an increased success with ingredients of natural origin, embracing the concepts of respect for your skin, or skin friendly emulsifiers.

This is due to 2 main aspects:

1. The need for developing formulas as much as possible compatible with the physiology of skin and its annexes, without any adverse effect or allergic potential.

2.The growing confidence of consumers in the beneficial properties provided by complex mixtures of natural ingredients.

Visit our store at Organic Products.

__________

Dec 06, 2024

how to know when to increase or decrease

Good day. I have been using Natpro for a couple of years. I am post menopausal. I was on HRT for 7 years. 2 years ago I started by replacing the progesterone

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Dec 04, 2024

We have added nicotinamide (vitamin B3)!

🌿We have added ‘nicotinamide’ (vitamin B3) to our trusted formula in our New 60ml Tubes!

🌿Read on to discover the benefits...

Nicotinamide infographic

Nicotinamide, also known as niacinamide, is a form of vitamin B3 that offers numerous benefits for skin health.

Key Benefits of Nicotinamide for Skin:

🌱 Enhances Skin Barrier Function... Nicotinamide helps build keratin, a protein essential for maintaining skin health. It strengthens the skin's lipid barrier, which locks in moisture and protects against environmental irritants, making it beneficial for all skin types, particularly those with conditions like eczema and rosacea.

🌱 Reduces Inflammation... This ingredient is known for its anti-inflammatory properties, which can help calm redness and irritation associated with acne, rosacea, and other inflammatory skin conditions. By reducing inflammation, nicotinamide can improve overall skin tone and texture.

🌱 Minimizes Pore Appearance... While it does not physically reduce pore size, nicotinamide can help minimize their appearance by keeping the skin smooth and regulating oil production, which prevents clogged pores and breakouts.

🌱 Treats Acne... Nicotinamide has been shown to be effective in treating acne vulgaris. Clinical studies indicate that topical nicotinamide gel can be as effective as traditional topical antibiotics in reducing acne lesions. Additionally, it decreases sebum production, which contributes to acne development.

🌱 Addresses Hyperpigmentation... Research suggests that formulations containing 5% nicotinamide can lighten dark spots and improve skin tone over time. This effect is attributed to increased collagen production and improved skin texture.

🌱 Protects Against Sun Damage... Nicotinamide enhances the skin's ability to repair DNA damage caused by UV exposure and may reduce the risk of certain types of skin cancer in high-risk individuals. However, it should not be used as a substitute for sunscreen.

🌱 Reduces Fine Lines and Wrinkles... Topical application of nicotinamide has been linked to improvements in fine lines and wrinkles due to its ability to stimulate collagen production and improve skin elasticity. Studies have reported significant improvements in signs of aging after consistent use over several weeks.

🌱 Increases Hydration... Nicotinamide helps reduce transepidermal water loss (TEWL), thereby increasing hydration levels in the upper layers of the skin. This makes it particularly beneficial for dry or dehydrated skin types.

Natpro Tube

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Dec 03, 2024

Cream Percentages

It is important to know the percentage of progesterone in the cream you choose to use...

cream percentages

You will be administering a different quantity of progesterone per gram of cream depending on the percentage strength of the progesterone in the cream.

For example Natpro is a 3.33% cream which means it has a concentration of 3333mg of progesterone. So for every gram of Natpro cream you are getting 33.33mg of progesterone.

***

Nov 28, 2024

Natpro Black Friday Sale!!

Natpro Black Friday

Just in time for Black Friday!

15% off our New Natpro Tube!

To take advantage of this launch offer please copy this coupon code…

natpro15

…then paste it into the ‘coupon code’ field on the order form after you click the ‘Add to Cart’ button.

The coupon is valid right now and expires midnight Saturday 30th November.

***

Nov 27, 2024

NEW Natpro 60ml Tubes!!

New Natpro Tube

🌿Reintroducing the Natpro 60ml Tubes!🌿

Due to countless requests for our tube option we are very happy to announce that we have brought it back into the Natpro family!

Not only are we re-launching it right now but we have introduced three modifications to the long established Natpro formula each of which bring small but meaningful improvements enhancing efficacy without changing the concentration of natural progesterone which remains at 3.33%.

Here are the modifications…

1• The emulsifier remains olive oil based but has been changed from ‘cetearyl olivate/sorbitan olivate’ to ‘sodium olivoil glutamate’

2• The stabilising agent ‘dehydroxanthan gum’ has been changed to ‘Xanthan Gum (&) Lecithin (&) Sclerotium Gum (&) Pullulan)’

3• We have added ‘nicotinamide’ (vitamin B3)

Read up on our formula modifications here.

Thank you for your continued support, we look forward to your feedback on the new tube!

***

Nov 18, 2024

Sleep deprived and miserable!

Hello, I have struggled with sleep issues for over 15 years. I can get to sleep fine, but I often wake up in the middle of the night and can't get back

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Nov 05, 2024

Natpro Stock In! 10% discount

Natpro dispenser inside golden arch

To our dear customers

As you may know we were stocked out of our Natpro dispenser for several days due to shipping delays so...

To compensate for the inconvenience and thank you for your loyalty and patience please use this coupon...

natpro10

...to claim your 10% discount on Natpro progesterone cream. Simply copy the coupon above and paste it into the coupon field after clicking the 'Add to Cart' button here...

Click here to claim your 10% now

•Offer is not limited by number of units per order.

•Offer expires midnight 19th November 2024.

Thank you and to your good health!

Organic Products & the Progesterone Therapy team

***

Oct 24, 2024

What about Progestelle? I used to purchase it here as the "gold standard"?

Hello again after a few years. When I first found this lovely sight years ago, Progestelle was available for purchase as a gold standard due to the simple

Continue reading "What about Progestelle? I used to purchase it here as the "gold standard"?"

Oct 17, 2024

Understanding the Role of Progesterone in Managing Cortisol Levels in Children

managing cortisol levels in children

Recent research highlights the substantial role of progesterone in managing cortisol levels, particularly in children, and even more specifically, in boys. Cortisol, recognized as the "stress hormone," significantly impacts children's behavior and stress levels, as demonstrated by hair cortisol concentration (HCC) studies. HCC offers a long-term perspective on cortisol levels, unlike blood or saliva tests that only reflect short-term fluctuations.

A study conducted on 11-year-olds in Spain revealed that higher HCC is associated with increased behavioral issues. This finding is particularly prominent in boys, suggesting a sex-specific susceptibility to stress-induced behavioral problems. These problems correlate with environmental stressors like noise and familial stress, particularly maternal stress, which in turn elevates cortisol levels in children.

Excess cortisol due to chronic stress can cause various negative health impacts. Therefore, maintaining balanced cortisol levels is crucial, and this is where progesterone plays a vital role. Progesterone is a naturally occurring hormone known for its anti-cortisol and anti-adrenaline properties. It directly counters cortisol's effects, offering a natural solution to lower these harmful levels, thereby reducing stress symptoms and enhancing overall well-being.

Progesterone works by enhancing the activity of GABA (gamma-aminobutyric acid), a key neurotransmitter that promotes relaxation and reduces anxiety, creating a calming effect. Furthermore, progesterone helps regulate the adrenal glands' activity, ensuring a balanced production of stress hormones like cortisol and adrenaline. Improving sleep quality is another benefit of progesterone, important for managing healthy cortisol rhythms and reducing stress.

These benefits of progesterone can be particularly helpful for children experiencing stress and related behavioral issues. By optimizing progesterone levels, reductions in anxiety, improvement in mood stability, fewer mood swings, and better sleep quality can be achieved when cortisol levels are managed effectively.

Using progesterone must be done under medical supervision to ensure proper dosing. It's crucial to integrate progesterone use with a comprehensive health strategy, which includes maintaining a balanced diet, regular physical activity, and incorporating stress-reduction practices like mindfulness or meditation.

In conclusion, progesterone stands as a promising tool in managing cortisol levels and mitigating its adverse effects on stress and behavior, particularly in boys. Its ability to balance stress responses highlights its importance in any holistic approach to children's well-being amidst the complexities of modern environmental and social stressors.

Reference:

Hair cortisol determinants in 11-year-old children: Environmental, social and individual factors

Analysis by Dr. Joseph Mercola: Is Elevated Cortisol Affecting Your Child's Behavior?, 9th October 2024

Oct 16, 2024

Stock Out

Natpro sold out

Due to high demand, we are currently out of stock of Natpro, progesterone cream. Don't worry, we’re working hard to restock! Stay tuned for updates, and thank you for your patience!

Sep 27, 2024

Managing PCOS as a Teen: Essential Steps to Take Control

PCOS teen

Polycystic Ovarian Syndrome (PCOS) is the most prevalent reproductive issue affecting young girls and women, with a incidence rate of 5-10%. Managing PCOS as a teenager can be challenging, but with the right approach and lifestyle changes, it’s possible to alleviate its symptoms and improve overall well-being. Here's a comprehensive guide on how to manage PCOS effectively during your teenage years.

•Understanding PCOS and Its Impact

What is PCOS?PCOS is a hormonal disorder characterized by the presence of multiple small cysts on the ovaries. It leads to a series of health issues due to hormonal imbalances involving insulin and androgens.

•Key Symptoms of PCOS:- Insulin resistance- Weight gain- High blood sugar levels- High triglycerides and androgens- Acne and excess hair growth- Anovulation (lack of ovulation)- Low progesterone levels

•Steps to Manage PCOS

1 Address Insulin Resistance:Insulin resistance is a core issue in PCOS. High insulin levels lead to elevated androgens, worsening the symptoms. Here’s how to manage it:**Diet: Focus on reducing insulin levels by consuming organic proteins and avoiding starchy carbs. Stick to non-starchy vegetables.**Supplements: Inositol, a B vitamin, has shown promise in reversing insulin resistance.

2. Hormonal Balance:Balancing hormones is crucial for managing PCOS.**Natural Progesterone Cream: Using 200-250mg/day can stabilize blood sugar and reduce androgen levels. It's vital to use this cream during the latter half of the menstrual cycle (days 14-28) to mimic natural progesterone production.**Avoid Synthetic Progesterone: It’s important to note that synthetic progesterone found in birth control pills can increase insulin resistance.

3. Nutritional Support:Certain nutrients can support overall health and help manage PCOS symptoms.**Essential Nutrients: Include vitamins B1, B2, B3, B6, B12, folic acid, biotin, and inositol in your daily intake.**Amino Acids and Supplements: L-glutamine, L-arginine, N-acetyl cysteine, and MCT oil can provide energy and help reduce cravings.**Probiotics: Probiotics such as Lactobacillus acidophilus and Bifidobacteria can aid digestion and hormonal balance.

4. Lifestyle Adjustments:Lifestyle changes play a significant role in managing PCOS.**Exercise Regularly: Physical activity helps in managing weight and improving insulin sensitivity.**Stress Management: High cortisol levels commonly found in PCOS can exacerbate symptoms. Practices like meditation and yoga can be beneficial.

5. Monitoring and Adjustments:Regular monitoring of hormone levels, including homocysteine, is essential for managing PCOS:**Homocysteine Testing: If levels are high, supplements like B2, B6, B12, folic acid, and zinc can help lower them.

•Conclusion

PCOS management in teens requires a multifaceted approach focusing on diet, supplements, hormone balance, and lifestyle changes. By addressing insulin resistance, balancing hormones naturally, and maintaining a healthy lifestyle, teens with PCOS can manage symptoms effectively and improve their quality of life. Always consult with a healthcare professional before starting any new treatment or supplement regime.

References

Sep 23, 2024

Using Progesterone Cream to Treat Infertility

progesterone for infertility

Progesterone, a hormone crucial to reproduction, derives its name from "pro-gestation," underscoring its fundamental role in pregnancy. While its importance in reproductive health is well-known, progesterone’s broader biological functions often remain underappreciated. This article aims to shed light on how using progesterone cream can potentially treat infertility.

*Understanding Progesterone

Progesterone is primarily secreted by the ovaries in females and the testes in males, with smaller amounts produced by the adrenal glands and brain. Unlike sex hormones like estrogen and testosterone, progesterone does not influence secondary sexual characteristics developed during puberty. Instead, it is a precursor to these sex hormones and others like cortisol.

*The Menstrual Cycle and Progesterone

The menstrual cycle consists of two main phases: the follicular phase, dominated by estrogen, and the luteal phase, dominated by progesterone. During the follicular phase, eggs develop, estrogen levels increase, and the uterine lining thickens. Mid-cycle, an LH surge triggers ovulation, releasing the egg. The latter half, or luteal phase, is when progesterone levels peak, preparing the uterus for potential implantation.

*Progesterone and Infertility

Low progesterone levels, particularly during the luteal phase, can make fertilization and implantation less likely. In many cases, women diagnosed as "infertile" might actually be experiencing issues with progesterone levels. Enhancing the early rise of progesterone post-ovulation is critical for successful implantation.

Using Progesterone Cream

*Dosage and Timing

For treating infertility, the dosage of progesterone cream ranges from 100-200mg/day, and in some instances, up to 400mg/day, depending on symptoms. The cream should be applied starting at ovulation or during the pre-ovulatory surge within the 50-hour window. Applying progesterone cream too early could act as a contraceptive, so timing is crucial.

*Monitoring Ovulation

To effectively use progesterone cream, tracking ovulation is essential. Methods include basal body temperature charting and using mini microscopes to observe changes in saliva or vaginal mucus patterns. During ovulation, a fern-like pattern emerges in the mucus, indicating the optimal time for progesterone application.

*Pregnancy and Progesterone

If conception occurs, continuing progesterone therapy is crucial for avoiding miscarriages. Should pregnancy be confirmed, the treatment should persist for at least the first three months, gradually tapering off only if advised. Abruptly stopping progesterone supplementation can result in miscarriage due to a sudden drop in hormone levels.

*Additional Considerations

•Vitamin D and Other Nutrients: Vitamin D, N-acetylcysteine, arginine, and inositol are vital for ovulation. A deficiency in these nutrients can lead to anovulatory cycles, hampering fertility.

•Managing Miscarriages and Pre-term Births: Increased progesterone levels can prevent miscarriages and pre-term births, particularly in cases of stress-induced cortisol spikes affecting progesterone levels.

•Preeclampsia: Low progesterone and vitamin D levels are significant risk factors for preeclampsia, a condition marked by high blood pressure and potential organ damage during pregnancy.

*Conclusion

Using progesterone cream under the right conditions can be an effective treatment for infertility, ensuring the necessary hormone levels are maintained for successful conception and pregnancy. As with any treatment, professional medical advice should be sought to tailor the approach to individual circumstances. By understanding and leveraging progesterone’s critical role, many women experiencing infertility can significantly improve their chances of conception.

See REFERENCES

Sep 06, 2024

Period every 5-7 days

Hello —almost 39 …been using progesterone cream for 5-6months 200mg or more daily but the last two months I started getting a period every 5-7 days that

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Sep 05, 2024

Can Progesterone Cream Cause Acne Breakouts?

progesterone cream for acne

Acne is a common inflammatory skin condition that primarily affects teenagers, but can persist into adulthood. Interestingly, it is uncommon among populations with natural, unprocessed diets, such as the Kitavan Islanders of Papua New Guinea and the Ache hunter-gatherers of Paraguay. This phenomenon is partly attributed to their lower glycaemic index diets, which help prevent insulin resistance and high androgen levels – two factors closely linked to acne.

•The Role of Hormones in Acne Formation

Hormones play a pivotal role in acne development. Elevated androgens like testosterone stimulate sebaceous glands to produce more sebum, an oily substance that can clog pores and foster bacterial growth, particularly by Propionibacterium acnes. This often leads to acne breakouts.

DHT (dihydrotestosterone), synthesized from testosterone by the enzyme 5-alpha reductase, is a particularly potent androgen involved in acne. Elevated levels of DHT in sebaceous glands can exacerbate acne symptoms. Progesterone is notable for its ability to inhibit 5-alpha reductase, thereby reducing DHT levels and potentially mitigating acne.

•Can Progesterone Cream Help or Worsen Acne?

Progesterone creams offer several skin benefits that might help in managing acne:

-Inhibits 5-alpha reductase: By limiting the activity of 5-alpha reductase, progesterone cream reduces DHT levels, potentially curbing sebum production.-Reduces androgen synthesis: Progesterone also inhibits the production of androgens within the body.-Reverses follicular keratosis: This refers to the abnormal shedding of skin cells, which can lead to clogged pores.-Reduces sebum excretion: Lower sebum levels mean less oil on the skin, reducing the likelihood of clogged pores and acne breakouts.

However, while progesterone cream has potential anti-acne properties, it can cause acne in some individuals, particularly if the formulation contains base ingredients that are comedogenic or irritating to the skin. It's crucial to check the ingredients list for harmful chemicals that could trigger acne or other skin reactions.

•Natural Remedies and Ingredients to Consider

In addition to progesterone, several natural ingredients are known for their anti-acne properties:

- Zinc: Inhibits 5-alpha reductase activity.- Vitamin B6: Enhances the effect of zinc.- Azelaic Acid: Found in wheat, barley, and rye, this natural plant acid effectively reduces the activity of acne-causing bacteria.- Vitamin D: Essential for overall skin health, with supplementation recommended for those deficient in this vitamin. Phototherapy utilizing violet and red light has also been beneficial.- Low-Glycaemic Load Diet: Diets with a low glycaemic index have been shown to improve both acne and insulin sensitivity.

•Conclusion

Progesterone cream can be an effective part of an acne treatment regimen due to its ability to inhibit DHT production and reduce sebum excretion. However, users should be diligent in checking the ingredient list for potential irritants. Combining progesterone cream with other natural remedies and maintaining a low-glycaemic diet may offer the best results for managing acne breakouts. Always consult with a healthcare provider before starting any new treatment to ensure it aligns with your specific skincare needs.

Reference

Sep 03, 2024

Is It Better to Take Progesterone Cream Orally or Topically?

oral or topical progesterone application

When it comes to administering progesterone, a crucial hormone for various bodily functions, there are several methods available. These include injections, IV transfusions, subcutaneous implants, suppositories, vaginal tablets, troches, buccal drops, oral capsules, gels, oils, and creams. Among these, the debate often centers on whether it is more effective to use progesterone cream orally or topically.

*Oral Application of Progesterone*

Oral capsules are an easily accessible and convenient method for administering progesterone. However, this route is generally considered the least effective. Much of the progesterone is destroyed by the gut and liver, this means that only a fraction of the administered dose reaches the bloodstream, diminishing the potential benefits. Ingredients in oral capsules can include peanut oil, gelatin, glycerin, lecithin, titanium dioxide, and various colorants, with a standard dosage around 100mg.

*Topical Application of Progesterone Cream*

Progesterone creams, on the other hand, are absorbed directly through the skin, bypassing the digestive system and liver. This allows for better bioavailability and effectiveness. The strength of progesterone creams varies, ranging from 1.5% to 10%, which means they can deliver between 15mg to 100mg of progesterone per gram or milliliter.

One significant advantage of progesterone creams is their versatility and ease of use. They don't require any special applicator, and application is painless. The cream can be applied to any area of the body, with the skin comprising 95% kerotinocytes that have ample progesterone receptor sites. This makes it effective for addressing localized pain such as menstrual cramps or migraines, as well as systemic absorption.

*Effectiveness and Safety*

Studies have shown that the progesterone in creams is absorbed well and enters circulation rapidly, sometimes as effectively as injections but without the associated discomfort and potential complications. Creams can be applied directly to areas of concern.

However, it's important to scrutinize the ingredients in progesterone creams. Some creams may contain harmful substances like liquid paraffin, parabens, phenoxyethanol, sodium lauryl sulphate, propylene glycol, fragrances, artificial colors, and PEG emulsifying waxes, which can include dioxane, a known carcinogen. Therefore, it is crucial to choose high-quality, safe formulations.

*Conclusion: Topical Creams Are Superior*

Given the drawbacks of oral progesterone, including reduced efficacy due to gut and liver metabolism, topical progesterone creams emerge as the superior option for most people. They offer better absorption, ease of use, and can be applied to specific areas for targeted relief. Always ensure you are using a high-quality product devoid of harmful additives.

For those exploring progesterone therapy, consulting with a healthcare provider to determine the most suitable method of application is crucial. Whether managing hormonal imbalances, alleviating pain, or addressing other health concerns, the right progesterone delivery system can make a significant difference in overall effectiveness.

Aug 26, 2024

Period for almost a month

38 using progesterone cream for 5-6months 200mg a day and suddenly have had my period for 17 days this month…I have it for about 7 days then a few day

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Aug 15, 2024

Breastfeeding oversupply

Hi there, I am currently battling oversupply and I have tried everything. Block feeding, pumping out the letdown before feeding, just pumping to decrease

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Aug 10, 2024

Overdue period

I've been using Natpro for over 6 months now (400mg per day - I'm under extreme long-term stress due to personal circumstances which, I'm sure, make matters

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Jul 30, 2024

Combating Estrogen Dominance with Natural Progesterone to Mitigate Cognitive Decline

progesterone to combat estrogen in cognitive decline

Estrogen dominance, a condition where estrogen levels are disproportionately high compared to progesterone, has long been associated with various health issues, including cognitive decline. Recent research, including a study published in JAMA Neurology, sheds new light on the potential role of pure estrogen receptor antagonists and aromatase inhibitors in mitigating the adverse effects of estrogen dominance, particularly concerning Alzheimer's Disease and Related Dementia (ADRD) risk in breast cancer patients.

Understanding Estrogen Dominance and Cognitive Health

Estrogen is often lauded for its role in various health functions, especially in women. However, excessive estrogen—unbalanced by adequate levels of progesterone—can lead to estrogen dominance. This imbalance has been linked to several health concerns, including breast cancer and cognitive decline.

The JAMA study highlights that while hormone-modulating therapies (HMT) like selective estrogen receptor modulators (SERMs) and aromatase inhibitors (AIs) can help reduce breast cancer recurrence by blocking estrogen's effects, they also touch on cognitive implications. Notably, more breast cancer survivors are experiencing cognitive decline, urging a reevaluation of estrogen's role and the potential benefits of natural progesterone.

The Protective Role of Natural Progesterone

Natural progesterone serves as a critical agent in countering estrogen's effects, offering several cognitive health benefits:

1. Estrogen Receptor Antagonist:Progesterone competes with estrogen at receptor sites, potentially mitigating the adverse effects of excessive estrogen on brain health.

2. Aromatase Inhibitor: Progesterone can inhibit aromatase, an enzyme that converts androgens into estrogen, thus reducing overall estrogen levels in the body.

3. Neuroprotective Properties: Independent of its anti-estrogenic effects, progesterone has demonstrated direct neuroprotective properties in animal studies and studies carried out on Traumatic Brain Injury cases at Emory University.

4. Anti-Inflammatory Effects: Given that inflammation plays a role in cognitive decline, progesterone's anti-inflammatory effects may help preserve brain health.

Implications for Breast Cancer Survivors

The JAMA study reveals nuanced findings regarding HMT's impact on ADRD risk among breast cancer survivors. The research shows that while HMT use is associated with a relative reduction in ADRD risk, the protective effect varies by age, race, and HMT type. Notably, younger women (aged 65-74) and Black women seem to derive more significant protective benefits, though these benefits diminish with age.

Given these findings, integrating natural progesterone into treatment plans could further enhance cognitive protection, especially in estrogen-dominant individuals. Natural progesterone can help balance the hormone effects, potentially reducing the cognitive risks associated with high estrogen levels.

A Call for Personalized Treatment Approaches

The study underscores the need for personalized treatment strategies that consider age, race, and individual hormone profiles. As more research sheds light on the benefits of natural progesterone, it may become an integral component of strategies aimed at mitigating cognitive decline in estrogen-dominant individuals, particularly among breast cancer survivors.

In conclusion, balancing estrogen with natural progesterone not only combats estrogen dominance but may also offer a promising approach to preserving cognitive health. As evidence mounts, healthcare providers and patients alike should consider the protective potential of natural progesterone in their holistic health strategies.

Jul 26, 2024

Progesterone cream through menopause

I’m in perimenopause …38 using 200-300mg of cream a day for about 5 months but have hit a point where I have extreme fatigue and breast pain and swelling

Continue reading "Progesterone cream through menopause"

Jul 26, 2024

Fatigue

Struggling with fatigue 5 months of 200-300mg…in perimenopause, but still having breast swelling and pain, and panic attacks. I’m scared it’s not going

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Jul 25, 2024

Natpro in Stock!

Natpro restock

To our valued customers, thank you for your patience and loyalty through this stock out, we are happy to report that stock is back in and available to order.

Jul 19, 2024

Anxiety

Hello around 39….using 200mg progesterone cream for about 4-5 months but noticed extreme anxiety, sleep issues and almost like a panic attack feeling when

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Jul 14, 2024

Breastfeeding and menstruating

Hi I’m 5 months postpartum and have been applying 300mg of progesterone cream daily. My period started today so I’m not sure if I should continue applying

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Jul 14, 2024

Progesterone Increase Side Effects

Hi there, I’ve been slowly increasing my progesterone cream from 100mg, taking day 14-28, now to daily for 6 weeks and have increased to 400mg. The thought

Continue reading " Progesterone Increase Side Effects "

Jul 10, 2024

Stock Out

sold out

We sincerely apologize for the inconvenience caused by the stock out of our progesterone cream. We understand how important this product is to your well-being, and we are working diligently to restock as quickly as possible.To show our appreciation for your patience and loyalty, we are offering a special discount on your next purchase. If you would like to take advantage of this offer, please send us an email to info@progesteronetherapy.com. We will make sure to notify you personally as soon as the product is back in stock.

Thank you for your understanding and continued support. We truly value your trust in us and look forward to serving you again soon.

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