Progesterone Blog

Nov 18, 2024

Sleep deprived and miserable!

Hello, I have struggled with sleep issues for over 15 years. I can get to sleep fine, but I often wake up in the middle of the night and can't get back

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Nov 05, 2024

Natpro Stock In! 10% discount

To our dear customers

As you may know we were stocked out of our Natpro dispenser for several days due to shipping delays so...

To compensate for the inconvenience and thank you for your loyalty and patience please use this coupon...

natpro10

...to claim your 10% discount on Natpro progesterone cream. Simply copy the coupon above and paste it into the coupon field after clicking the 'Add to Cart' button here...

Click here to claim your 10% now

•Offer is not limited by number of units per order.

•Offer expires midnight 19th November 2024.

Thank you and to your good health!

Organic Products & the Progesterone Therapy team

***

Oct 24, 2024

What about Progestelle? I used to purchase it here as the "gold standard"?

Hello again after a few years. When I first found this lovely sight years ago, Progestelle was available for purchase as a gold standard due to the simple

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Oct 17, 2024

Understanding the Role of Progesterone in Managing Cortisol Levels in Children

Recent research highlights the substantial role of progesterone in managing cortisol levels, particularly in children, and even more specifically, in boys. Cortisol, recognized as the "stress hormone," significantly impacts children's behavior and stress levels, as demonstrated by hair cortisol concentration (HCC) studies. HCC offers a long-term perspective on cortisol levels, unlike blood or saliva tests that only reflect short-term fluctuations.

A study conducted on 11-year-olds in Spain revealed that higher HCC is associated with increased behavioral issues. This finding is particularly prominent in boys, suggesting a sex-specific susceptibility to stress-induced behavioral problems. These problems correlate with environmental stressors like noise and familial stress, particularly maternal stress, which in turn elevates cortisol levels in children.

Excess cortisol due to chronic stress can cause various negative health impacts. Therefore, maintaining balanced cortisol levels is crucial, and this is where progesterone plays a vital role. Progesterone is a naturally occurring hormone known for its anti-cortisol and anti-adrenaline properties. It directly counters cortisol's effects, offering a natural solution to lower these harmful levels, thereby reducing stress symptoms and enhancing overall well-being.

Progesterone works by enhancing the activity of GABA (gamma-aminobutyric acid), a key neurotransmitter that promotes relaxation and reduces anxiety, creating a calming effect. Furthermore, progesterone helps regulate the adrenal glands' activity, ensuring a balanced production of stress hormones like cortisol and adrenaline. Improving sleep quality is another benefit of progesterone, important for managing healthy cortisol rhythms and reducing stress.

These benefits of progesterone can be particularly helpful for children experiencing stress and related behavioral issues. By optimizing progesterone levels, reductions in anxiety, improvement in mood stability, fewer mood swings, and better sleep quality can be achieved when cortisol levels are managed effectively.

Using progesterone must be done under medical supervision to ensure proper dosing. It's crucial to integrate progesterone use with a comprehensive health strategy, which includes maintaining a balanced diet, regular physical activity, and incorporating stress-reduction practices like mindfulness or meditation.

In conclusion, progesterone stands as a promising tool in managing cortisol levels and mitigating its adverse effects on stress and behavior, particularly in boys. Its ability to balance stress responses highlights its importance in any holistic approach to children's well-being amidst the complexities of modern environmental and social stressors.

Reference:

Hair cortisol determinants in 11-year-old children: Environmental, social and individual factors

Analysis by Dr. Joseph Mercola: Is Elevated Cortisol Affecting Your Child's Behavior?, 9th October 2024

Oct 16, 2024

Stock Out

Due to high demand, we are currently out of stock of Natpro, progesterone cream. Don't worry, we’re working hard to restock! Stay tuned for updates, and thank you for your patience!

Sep 27, 2024

Managing PCOS as a Teen: Essential Steps to Take Control

Polycystic Ovarian Syndrome (PCOS) is the most prevalent reproductive issue affecting young girls and women, with a incidence rate of 5-10%. Managing PCOS as a teenager can be challenging, but with the right approach and lifestyle changes, it’s possible to alleviate its symptoms and improve overall well-being. Here's a comprehensive guide on how to manage PCOS effectively during your teenage years.

•Understanding PCOS and Its Impact

What is PCOS?PCOS is a hormonal disorder characterized by the presence of multiple small cysts on the ovaries. It leads to a series of health issues due to hormonal imbalances involving insulin and androgens.

•Key Symptoms of PCOS:- Insulin resistance- Weight gain- High blood sugar levels- High triglycerides and androgens- Acne and excess hair growth- Anovulation (lack of ovulation)- Low progesterone levels

•Steps to Manage PCOS

1 Address Insulin Resistance:Insulin resistance is a core issue in PCOS. High insulin levels lead to elevated androgens, worsening the symptoms. Here’s how to manage it:**Diet: Focus on reducing insulin levels by consuming organic proteins and avoiding starchy carbs. Stick to non-starchy vegetables.**Supplements: Inositol, a B vitamin, has shown promise in reversing insulin resistance.

2. Hormonal Balance:Balancing hormones is crucial for managing PCOS.**Natural Progesterone Cream: Using 200-250mg/day can stabilize blood sugar and reduce androgen levels. It's vital to use this cream during the latter half of the menstrual cycle (days 14-28) to mimic natural progesterone production.**Avoid Synthetic Progesterone: It’s important to note that synthetic progesterone found in birth control pills can increase insulin resistance.

3. Nutritional Support:Certain nutrients can support overall health and help manage PCOS symptoms.**Essential Nutrients: Include vitamins B1, B2, B3, B6, B12, folic acid, biotin, and inositol in your daily intake.**Amino Acids and Supplements: L-glutamine, L-arginine, N-acetyl cysteine, and MCT oil can provide energy and help reduce cravings.**Probiotics: Probiotics such as Lactobacillus acidophilus and Bifidobacteria can aid digestion and hormonal balance.

4. Lifestyle Adjustments:Lifestyle changes play a significant role in managing PCOS.**Exercise Regularly: Physical activity helps in managing weight and improving insulin sensitivity.**Stress Management: High cortisol levels commonly found in PCOS can exacerbate symptoms. Practices like meditation and yoga can be beneficial.

5. Monitoring and Adjustments:Regular monitoring of hormone levels, including homocysteine, is essential for managing PCOS:**Homocysteine Testing: If levels are high, supplements like B2, B6, B12, folic acid, and zinc can help lower them.

•Conclusion

PCOS management in teens requires a multifaceted approach focusing on diet, supplements, hormone balance, and lifestyle changes. By addressing insulin resistance, balancing hormones naturally, and maintaining a healthy lifestyle, teens with PCOS can manage symptoms effectively and improve their quality of life. Always consult with a healthcare professional before starting any new treatment or supplement regime.

References

Sep 23, 2024

Using Progesterone Cream to Treat Infertility

Progesterone, a hormone crucial to reproduction, derives its name from "pro-gestation," underscoring its fundamental role in pregnancy. While its importance in reproductive health is well-known, progesterone’s broader biological functions often remain underappreciated. This article aims to shed light on how using progesterone cream can potentially treat infertility.

*Understanding Progesterone

Progesterone is primarily secreted by the ovaries in females and the testes in males, with smaller amounts produced by the adrenal glands and brain. Unlike sex hormones like estrogen and testosterone, progesterone does not influence secondary sexual characteristics developed during puberty. Instead, it is a precursor to these sex hormones and others like cortisol.

*The Menstrual Cycle and Progesterone

The menstrual cycle consists of two main phases: the follicular phase, dominated by estrogen, and the luteal phase, dominated by progesterone. During the follicular phase, eggs develop, estrogen levels increase, and the uterine lining thickens. Mid-cycle, an LH surge triggers ovulation, releasing the egg. The latter half, or luteal phase, is when progesterone levels peak, preparing the uterus for potential implantation.

*Progesterone and Infertility

Low progesterone levels, particularly during the luteal phase, can make fertilization and implantation less likely. In many cases, women diagnosed as "infertile" might actually be experiencing issues with progesterone levels. Enhancing the early rise of progesterone post-ovulation is critical for successful implantation.

Using Progesterone Cream

*Dosage and Timing

For treating infertility, the dosage of progesterone cream ranges from 100-200mg/day, and in some instances, up to 400mg/day, depending on symptoms. The cream should be applied starting at ovulation or during the pre-ovulatory surge within the 50-hour window. Applying progesterone cream too early could act as a contraceptive, so timing is crucial.

*Monitoring Ovulation

To effectively use progesterone cream, tracking ovulation is essential. Methods include basal body temperature charting and using mini microscopes to observe changes in saliva or vaginal mucus patterns. During ovulation, a fern-like pattern emerges in the mucus, indicating the optimal time for progesterone application.

*Pregnancy and Progesterone

If conception occurs, continuing progesterone therapy is crucial for avoiding miscarriages. Should pregnancy be confirmed, the treatment should persist for at least the first three months, gradually tapering off only if advised. Abruptly stopping progesterone supplementation can result in miscarriage due to a sudden drop in hormone levels.

*Additional Considerations

•Vitamin D and Other Nutrients: Vitamin D, N-acetylcysteine, arginine, and inositol are vital for ovulation. A deficiency in these nutrients can lead to anovulatory cycles, hampering fertility.

•Managing Miscarriages and Pre-term Births: Increased progesterone levels can prevent miscarriages and pre-term births, particularly in cases of stress-induced cortisol spikes affecting progesterone levels.

•Preeclampsia: Low progesterone and vitamin D levels are significant risk factors for preeclampsia, a condition marked by high blood pressure and potential organ damage during pregnancy.

*Conclusion

Using progesterone cream under the right conditions can be an effective treatment for infertility, ensuring the necessary hormone levels are maintained for successful conception and pregnancy. As with any treatment, professional medical advice should be sought to tailor the approach to individual circumstances. By understanding and leveraging progesterone’s critical role, many women experiencing infertility can significantly improve their chances of conception.

See REFERENCES

Sep 06, 2024

Period every 5-7 days

Hello —almost 39 …been using progesterone cream for 5-6months 200mg or more daily but the last two months I started getting a period every 5-7 days that

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Sep 05, 2024

Can Progesterone Cream Cause Acne Breakouts?

Acne is a common inflammatory skin condition that primarily affects teenagers, but can persist into adulthood. Interestingly, it is uncommon among populations with natural, unprocessed diets, such as the Kitavan Islanders of Papua New Guinea and the Ache hunter-gatherers of Paraguay. This phenomenon is partly attributed to their lower glycaemic index diets, which help prevent insulin resistance and high androgen levels – two factors closely linked to acne.

•The Role of Hormones in Acne Formation

Hormones play a pivotal role in acne development. Elevated androgens like testosterone stimulate sebaceous glands to produce more sebum, an oily substance that can clog pores and foster bacterial growth, particularly by Propionibacterium acnes. This often leads to acne breakouts.

DHT (dihydrotestosterone), synthesized from testosterone by the enzyme 5-alpha reductase, is a particularly potent androgen involved in acne. Elevated levels of DHT in sebaceous glands can exacerbate acne symptoms. Progesterone is notable for its ability to inhibit 5-alpha reductase, thereby reducing DHT levels and potentially mitigating acne.

•Can Progesterone Cream Help or Worsen Acne?

Progesterone creams offer several skin benefits that might help in managing acne:

-Inhibits 5-alpha reductase: By limiting the activity of 5-alpha reductase, progesterone cream reduces DHT levels, potentially curbing sebum production.-Reduces androgen synthesis: Progesterone also inhibits the production of androgens within the body.-Reverses follicular keratosis: This refers to the abnormal shedding of skin cells, which can lead to clogged pores.-Reduces sebum excretion: Lower sebum levels mean less oil on the skin, reducing the likelihood of clogged pores and acne breakouts.

However, while progesterone cream has potential anti-acne properties, it can cause acne in some individuals, particularly if the formulation contains base ingredients that are comedogenic or irritating to the skin. It's crucial to check the ingredients list for harmful chemicals that could trigger acne or other skin reactions.

•Natural Remedies and Ingredients to Consider

In addition to progesterone, several natural ingredients are known for their anti-acne properties:

- Zinc: Inhibits 5-alpha reductase activity.- Vitamin B6: Enhances the effect of zinc.- Azelaic Acid: Found in wheat, barley, and rye, this natural plant acid effectively reduces the activity of acne-causing bacteria.- Vitamin D: Essential for overall skin health, with supplementation recommended for those deficient in this vitamin. Phototherapy utilizing violet and red light has also been beneficial.- Low-Glycaemic Load Diet: Diets with a low glycaemic index have been shown to improve both acne and insulin sensitivity.

•Conclusion

Progesterone cream can be an effective part of an acne treatment regimen due to its ability to inhibit DHT production and reduce sebum excretion. However, users should be diligent in checking the ingredient list for potential irritants. Combining progesterone cream with other natural remedies and maintaining a low-glycaemic diet may offer the best results for managing acne breakouts. Always consult with a healthcare provider before starting any new treatment to ensure it aligns with your specific skincare needs.

Reference

Sep 03, 2024

Is It Better to Take Progesterone Cream Orally or Topically?

When it comes to administering progesterone, a crucial hormone for various bodily functions, there are several methods available. These include injections, IV transfusions, subcutaneous implants, suppositories, vaginal tablets, troches, buccal drops, oral capsules, gels, oils, and creams. Among these, the debate often centers on whether it is more effective to use progesterone cream orally or topically.

*Oral Application of Progesterone*

Oral capsules are an easily accessible and convenient method for administering progesterone. However, this route is generally considered the least effective. Much of the progesterone is destroyed by the gut and liver, this means that only a fraction of the administered dose reaches the bloodstream, diminishing the potential benefits. Ingredients in oral capsules can include peanut oil, gelatin, glycerin, lecithin, titanium dioxide, and various colorants, with a standard dosage around 100mg.

*Topical Application of Progesterone Cream*

Progesterone creams, on the other hand, are absorbed directly through the skin, bypassing the digestive system and liver. This allows for better bioavailability and effectiveness. The strength of progesterone creams varies, ranging from 1.5% to 10%, which means they can deliver between 15mg to 100mg of progesterone per gram or milliliter.

One significant advantage of progesterone creams is their versatility and ease of use. They don't require any special applicator, and application is painless. The cream can be applied to any area of the body, with the skin comprising 95% kerotinocytes that have ample progesterone receptor sites. This makes it effective for addressing localized pain such as menstrual cramps or migraines, as well as systemic absorption.

*Effectiveness and Safety*

Studies have shown that the progesterone in creams is absorbed well and enters circulation rapidly, sometimes as effectively as injections but without the associated discomfort and potential complications. Creams can be applied directly to areas of concern.

However, it's important to scrutinize the ingredients in progesterone creams. Some creams may contain harmful substances like liquid paraffin, parabens, phenoxyethanol, sodium lauryl sulphate, propylene glycol, fragrances, artificial colors, and PEG emulsifying waxes, which can include dioxane, a known carcinogen. Therefore, it is crucial to choose high-quality, safe formulations.

*Conclusion: Topical Creams Are Superior*

Given the drawbacks of oral progesterone, including reduced efficacy due to gut and liver metabolism, topical progesterone creams emerge as the superior option for most people. They offer better absorption, ease of use, and can be applied to specific areas for targeted relief. Always ensure you are using a high-quality product devoid of harmful additives.

For those exploring progesterone therapy, consulting with a healthcare provider to determine the most suitable method of application is crucial. Whether managing hormonal imbalances, alleviating pain, or addressing other health concerns, the right progesterone delivery system can make a significant difference in overall effectiveness.

Aug 26, 2024

Period for almost a month

38 using progesterone cream for 5-6months 200mg a day and suddenly have had my period for 17 days this month…I have it for about 7 days then a few day

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Aug 15, 2024

Breastfeeding oversupply

Hi there, I am currently battling oversupply and I have tried everything. Block feeding, pumping out the letdown before feeding, just pumping to decrease

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Aug 10, 2024

Overdue period

I've been using Natpro for over 6 months now (400mg per day - I'm under extreme long-term stress due to personal circumstances which, I'm sure, make matters

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Jul 30, 2024

Combating Estrogen Dominance with Natural Progesterone to Mitigate Cognitive Decline

Estrogen dominance, a condition where estrogen levels are disproportionately high compared to progesterone, has long been associated with various health issues, including cognitive decline. Recent research, including a study published in JAMA Neurology, sheds new light on the potential role of pure estrogen receptor antagonists and aromatase inhibitors in mitigating the adverse effects of estrogen dominance, particularly concerning Alzheimer's Disease and Related Dementia (ADRD) risk in breast cancer patients.

Understanding Estrogen Dominance and Cognitive Health

Estrogen is often lauded for its role in various health functions, especially in women. However, excessive estrogen—unbalanced by adequate levels of progesterone—can lead to estrogen dominance. This imbalance has been linked to several health concerns, including breast cancer and cognitive decline.

The JAMA study highlights that while hormone-modulating therapies (HMT) like selective estrogen receptor modulators (SERMs) and aromatase inhibitors (AIs) can help reduce breast cancer recurrence by blocking estrogen's effects, they also touch on cognitive implications. Notably, more breast cancer survivors are experiencing cognitive decline, urging a reevaluation of estrogen's role and the potential benefits of natural progesterone.

The Protective Role of Natural Progesterone

Natural progesterone serves as a critical agent in countering estrogen's effects, offering several cognitive health benefits:

1. Estrogen Receptor Antagonist:Progesterone competes with estrogen at receptor sites, potentially mitigating the adverse effects of excessive estrogen on brain health.

2. Aromatase Inhibitor: Progesterone can inhibit aromatase, an enzyme that converts androgens into estrogen, thus reducing overall estrogen levels in the body.

3. Neuroprotective Properties: Independent of its anti-estrogenic effects, progesterone has demonstrated direct neuroprotective properties in animal studies and studies carried out on Traumatic Brain Injury cases at Emory University.

4. Anti-Inflammatory Effects: Given that inflammation plays a role in cognitive decline, progesterone's anti-inflammatory effects may help preserve brain health.

Implications for Breast Cancer Survivors

The JAMA study reveals nuanced findings regarding HMT's impact on ADRD risk among breast cancer survivors. The research shows that while HMT use is associated with a relative reduction in ADRD risk, the protective effect varies by age, race, and HMT type. Notably, younger women (aged 65-74) and Black women seem to derive more significant protective benefits, though these benefits diminish with age.

Given these findings, integrating natural progesterone into treatment plans could further enhance cognitive protection, especially in estrogen-dominant individuals. Natural progesterone can help balance the hormone effects, potentially reducing the cognitive risks associated with high estrogen levels.

A Call for Personalized Treatment Approaches

The study underscores the need for personalized treatment strategies that consider age, race, and individual hormone profiles. As more research sheds light on the benefits of natural progesterone, it may become an integral component of strategies aimed at mitigating cognitive decline in estrogen-dominant individuals, particularly among breast cancer survivors.

In conclusion, balancing estrogen with natural progesterone not only combats estrogen dominance but may also offer a promising approach to preserving cognitive health. As evidence mounts, healthcare providers and patients alike should consider the protective potential of natural progesterone in their holistic health strategies.

Jul 26, 2024

Progesterone cream through menopause

I’m in perimenopause …38 using 200-300mg of cream a day for about 5 months but have hit a point where I have extreme fatigue and breast pain and swelling

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Jul 26, 2024

Fatigue

Struggling with fatigue 5 months of 200-300mg…in perimenopause, but still having breast swelling and pain, and panic attacks. I’m scared it’s not going

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Jul 25, 2024

Natpro in Stock!

To our valued customers, thank you for your patience and loyalty through this stock out, we are happy to report that stock is back in and available to order.

Jul 19, 2024

Anxiety

Hello around 39….using 200mg progesterone cream for about 4-5 months but noticed extreme anxiety, sleep issues and almost like a panic attack feeling when

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Jul 14, 2024

Breastfeeding and menstruating

Hi I’m 5 months postpartum and have been applying 300mg of progesterone cream daily. My period started today so I’m not sure if I should continue applying

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Jul 14, 2024

Progesterone Increase Side Effects

Hi there, I’ve been slowly increasing my progesterone cream from 100mg, taking day 14-28, now to daily for 6 weeks and have increased to 400mg. The thought

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Jul 10, 2024

Stock Out

We sincerely apologize for the inconvenience caused by the stock out of our progesterone cream. We understand how important this product is to your well-being, and we are working diligently to restock as quickly as possible.To show our appreciation for your patience and loyalty, we are offering a special discount on your next purchase. If you would like to take advantage of this offer, please send us an email to info@progesteronetherapy.com. We will make sure to notify you personally as soon as the product is back in stock.

Thank you for your understanding and continued support. We truly value your trust in us and look forward to serving you again soon.

Jul 03, 2024

Understanding and Managing Estrogen Dominance

Estrogen dominance, a condition where estrogen levels are excessively high relative to progesterone, can cause various adverse symptoms in both men and women. Women on HRT (hormone replacement therapy) or the Pill often experience this due to low progesterone levels.

Symptoms of Estrogen Dominance:

- Aches and pains- Abnormal bleeding- Bloating and weight gain- Breast tenderness- Constipation- Dizziness- Headaches and migraines- Mood swings- Fatigue and chronic tiredness- Skin issues (acne/melasma)- Hot flushes

Progesterone Therapy:

Progesterone therapy can initially worsen symptoms by making estrogen temporarily dominant as they target the same receptor sites, but over time, progesterone will balance your estrogen levels and alleviate symptoms. Women typically need 100-200mg/day, but severe symptoms might require up to 400mg/day. Men usually benefit from 10-20mg/day, increasing to 100mg/day if needed.

Management Tips:

- Gradually adjust progesterone levels once symptoms improve.- Stress and large meals can lower progesterone sharply—adjust dosage during stressful periods.- Ensure adequate vitamin D intake as a deficiency can reduce progesterone efficacy.

Lifestyle Considerations:

- Avoid large meals, all forms of estrogen, oxidised fats, processed dairy, and tap water.- Opt for organic, hormone-free products and filtered water.- Check labels on food and cosmetics to avoid endocrine disruptors.

For those on HRT or the Pill, consider tapering off gradually while using progesterone to ease symptoms.

For more information see our page on Estrogen Dominance.

Jun 28, 2024

The Power of Natural Progesterone: A Comprehensive Remedy for Health Issues

Progesterone, one of the oldest known hormones on Earth, is fundamental to the well-being of all vertebrates, including fish, reptiles, birds, and mammals. Despite its association with female reproductive health, natural progesterone is crucial for both sexes and all age groups, helping regulate blood sugar, develop intelligence, build bones, and facilitate brain activity. It acts as a precursor to other vital hormones like oestrogen and testosterone.

Discovered in 1934 by William Allen and George Corner, and later synthesised from the plant steroid diosgenin in 1943 by Russell Marker, natural progesterone has a broad spectrum of therapeutic potentials. It addresses health issues ranging from postnatal psychosis and traumatic brain injuries to myopathy, peripheral neuropathy, cancer, pregnancy complications, migraines, menopause symptoms, and more.

Our bodies produce progesterone primarily in the ovaries and testes, with minor contributions from the adrenal glands, brain, and glial cells. However, confusion often arises between natural progesterone and synthetic versions like progestins and progestogens. Unlike natural progesterone, these synthetic counterparts have altered molecular structures, making them patentable but also potentially toxic. They are linked to numerous side effects such as increased risk of congenital abnormalities, fluid retention, epilepsy, asthma, depression, cardiac and renal dysfunction, and even cancer.

One essential lesson is the profound impact of even minor differences in molecular structures on the body's functioning. For instance, the structural distinctions between estradiol and testosterone are minute but determine significant physiological traits like gender.

Additionally, so-called "yam extracts" or "yam creams," which contain the plant steroid diosgenin, cannot be converted by the body into progesterone. While they may offer some adaptogenic benefits, they do not correct hormonal imbalances.

Natural progesterone's essential role in health and life itself cannot be overstated. For further in-depth information and to explore the science behind natural progesterone, please visit our main website. Learning about this crucial hormone can open doors to better health and well-being.

Jun 25, 2024

Does Progesterone Cream Help with Endometriosis Symptoms?

Endometriosis is a debilitating condition affecting approximately 20% of women worldwide during their reproductive years. This condition occurs when endometrial cells, typically lining the uterus, are found growing in other areas of the body, including the pelvic region, ovaries, fallopian tubes, and even the brain and lungs. These ectopic endometrial cells respond to hormonal changes in the same way as those in the uterus, leading to severe pain and other symptoms such as lower back pain, painful intercourse, bowel and urinary discomfort, fatigue, and infertility.

Research has highlighted that women with endometriosis tend to have insufficient progesterone production and a shorter luteal phase. This imbalance can result in the endometrium not responding adequately to the progesterone stimulus, necessitating supplemental progesterone.

The Role of Progesterone in Managing Endometriosis

Progesterone is a hormone essential for regulating the menstrual cycle and maintaining pregnancy. It also has an anti-proliferative effect on endometrial tissue, counteracting the growth-promoting effects of oestrogen. This makes progesterone a potentially valuable treatment for endometriosis. Supplemental progesterone, in the form of natural progesterone cream, can help alleviate symptoms by providing the hormonal support that the body lacks.

How to Use Progesterone Cream for Endometriosis

Administering natural progesterone cream can be particularly beneficial for managing endometriosis symptoms. The usual dosage ranges from 100-200mg/day. It is advisable to start with a higher dose to overcome the initial resistance, with some severe cases requiring even more.

For those with regular menstrual cycles, the cream should be applied during the last 14 days of the cycle, from ovulation to the onset of menstruation. In the absence of a regular cycle or in cases of severe pain, using the cream daily for the first two to three months is recommended. This approach involves rubbing the cream over the painful areas. Once symptoms improve, a cyclic method can be adopted to help recalibrate the body's natural cycle.

Complementary Treatments for Endometriosis

While progesterone cream offers relief, addressing oxidative stress is crucial since it plays a role in the disease's progression. Therefore, incorporating high doses of antioxidants such as N-acetyl cysteine (NAC) and vitamin D is vital. NAC helps in the cellular synthesis of glutathione, an essential antioxidant, with a recommended dosage of at least 5000mg/day.

Vitamin D deficiency is common and exacerbates endometriosis symptoms. Testing for vitamin D levels and maintaining a minimum intake of 5000IU/day is essential, with higher doses needed in cases of severe deficiency.

Conclusion

Endometriosis remains a complex condition with no definitive cure. However, the use of natural progesterone cream can significantly improve symptoms for many women. When used correctly, it helps restore hormonal balance and reduce the growth of ectopic endometrial tissue. Coupled with antioxidant therapy and vitamin D supplementation, natural progesterone offers a holistic approach to managing endometriosis symptoms. Always consult with a healthcare provider for personalised advice and treatment plans.

Jun 16, 2024

Endometrial Hyperplasia

My doctor wants to put me on Prometrium to treat endometrial hyperplasia due to estrogen dominance to shrink the thickness. I am uncertain about taking

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Jun 15, 2024

Kathy

I’ve started using bio identical progesterone pills and worked my way up to 800mg. 200 morning, 200 lunchtime and 400 before bed. I don’t have very high

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Jun 11, 2024

NAC

Hi I’ve not been on this site for few years but have been using progesterone cream for 16 years 300 to 500 mg a day with very few breaks along with 5000

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Jun 03, 2024

Is it safe to use progesterone cream while pregnant?

During pregnancy, hormonal balance is crucial for the health of the mother and the developing baby. Progesterone, a key hormone in maintaining pregnancy, naturally increases to support the growing foetus. Given its importance, it's understandable why some women consider using progesterone cream, especially when facing hormonal imbalances or a history of miscarriages.

Progesterone helps prepare the uterus for embryo implantation and supports early pregnancy by maintaining the uterine lining. This hormone is produced by the ovaries and later by the placenta, which can increase progesterone levels up to 50 times those found in non-pregnant women. Despite this natural increase, some women continue to experience adverse symptoms throughout their pregnancy, which might indicate insufficient progesterone levels, potentially increasing the risk of complications.

Medical professionals might recommend progesterone supplementation for women with a history of PMS, habitual miscarriages, or those undergoing treatments like in vitro fertilization (IVF). For those considering pregnancy, it's often advised to start progesterone a few days post-conception and continue throughout pregnancy. This can help alleviate common symptoms like nausea, vomiting, and headaches, which are typical in early pregnancy due to hormonal fluctuations.

If symptoms such as excessive nausea or extreme fatigue persist, the progesterone dose may be increased until relief is found. This adjustment helps until the placenta is fully functional, around the fourth month, when it takes over progesterone production. Conversely, if symptoms are mild or absent, the progesterone dose can be gradually reduced. Do not discontinue using progesterone whilst pregnant as a sudden drop may lead to miscarriage.

Progesterone plays a crucial role in preventing miscarriages, particularly early in the pregnancy. In cases of a defective luteal phase—when the interval between ovulation and menstruation is too short for proper implantation— supplementing with progesterone cream can be critical. By extending the luteal phase, progesterone therapy supports the embryo's successful implantation and early growth, reducing the risk of miscarriage.

Progesterone may also play a role in managing pre-eclampsia risks. This condition, characterised by high blood pressure and protein in the urine in late pregnancy, can pose serious risks to both mother and child. As observed in studies, symptoms of pre-eclampsia mirror severe PMS, and supplemental progesterone has shown potential in reducing these symptoms.

Postnatal depression (PND) is another area where progesterone therapy has shown promise. Providing adequate progesterone post-delivery may help reduce the risk of PND, especially in women predisposed to severe PMS or those who have experienced PND in previous pregnancies.

Using progesterone cream during pregnancy can be highly beneficial for women with hormonal imbalances, a history of miscarriages, or those undergoing fertility treatments. The decision to use progesterone cream should always be based on individual health needs and under the guidance of a medical professional who understands natural hormonal therapies, to ensure the best outcomes for both mother and baby.

Jun 01, 2024

Progesterone Cream Pecentage

Hi, Just had a question regarding progesterone cream percentages. As mentioned on the site, Natpro is A 3.33% progesterone cream. As I await an order arrival,

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May 09, 2024

Natpro dosage for a 42-year-old with a light menstrual cycle monthly

Hello Wray, I recently purchased Natpro, as I have been trying to come off of oral progesterone because of the sedative effects. I'm not sure if I'm going

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