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PLEASE HELP

by catherine
(DK-europe)

Hej Wray

I came across your site and I really need help:

My story is very long but I will shorten it by telling how situation is now.

depression since 15 year old.

I am 36 years old, have three children and currently having a severe kind of estrogen dominance. I am totally paralyzed mentally and physically and suicidal and only waiting for a miracle relieving my symptoms.'

Earlier I have had 3 surgery for removing mild endometriosis.
I have during the past 2 years used serenity progesterone 1/8 teaspoon twice daily and only for a couple of days because of worsening.

the last 3 month my period has been messed but normally I have it every 26-28 days

I am allergic to even small amounts of medication, foods act. very sensitive in all ways

I currantly take 25 mg zoloft
and 25 ug D3
20 mg omeprazole antacid

I am constantly in pain and depressed. My stomach hurts every minute of the day. joint aches and only stock to my sofa all day.

After I have read your site I have ordered natpro and would like to give it a chance as this is my last hope but need advice on dosing and somebody to follow me. please help

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Dec 08, 2012
 PLEASE HELP
by: Wray

Hi Catherine You poor thing. I was suicidal at one point, but was ±47, so had no young children to look after. Progesterone did help me, but I feel you would need help from the natural antidepressants too. Please see our page on Anxiety, it gives a list of them. They all help, slowly but surely. Endometriosis is caused by oxidative stress, large amounts of antioxidants are needed to reverse it. I've also found 500mg/day progesterone is needed particularly if pain is present. So the 1/4tsp of serenity would have only made matters worse as you found. It would be giving you about 26mg/day progesterone. Progesterone can upset the cycle when first using it, making it either earlier or later than normal. It's nothing to worry about as it will settle in time. You're not taking enough vitamin D, 25mcg is giving you only 1000iu's per day. The minimum should be 5000iu's or 125mcg. But I feel you would need at least 10,000, if not 20,000 iu to begin with. A lack of vitamin D reduces the benefits of progesterone, plus it causes depression, see here, here, here, here, here. and here. It also helps pain too, see here, here, here, here and here. Please have a test done. Continued below
Dec 08, 2012
 PLEASE HELP Part 2
by: Wray

Hi Catherine For more info on vitamin D levels, test kits etc see the Vitamin D Council, GrassrootsHealth and Birmingham Hospital. Blood levels should be 70-100ng/ml (175-250nmol/L) and not the 30ng/ml (75nmol/L) most labs and doctors regard as adequate. The minimum daily dose should be 5000iu's per day, although recent research indicates it should be 10,000iu's per day, see here. It also helps the gut, see here, here and here. Vitamin D is also low if allergies are present, see here, here and here. I'm not sure if you've read our page on How to use progesterone cream, but it does explain how to use it. Briefly enough has to be used to help, and it should be used a minimum of twice a day. Some women use it hourly if they have severe symptoms. I'm more than happy to answer questions should they arise. Plus you might like to get in touch with our distributor in London. Her name is Julienne and you can contact her via her website here. She is also a registered EFT therapist, a wonderful therapy you might consider doing. Take care Wray
Dec 08, 2012
 There is Hope
by: Sage

Catherine I am so glad you found Wray's website. She will respond soon. Please know that you have come to the right place and you will receive the help you need.
What I can share with you is that I have been on a high dose 1000mg/day progesterone now for 21 days and this has made life tolerable. I had severe estrogen dominance and life long depression too. Symptoms are SO much better though it does take time to resolve I know that I am finally on the path to better health and most important a sense of well-being.
Wray will ask if you have had a VIt D test. It sounds like your levels are probably pretty low and the dose you are taking is not nearly enough. I am taking 20,000 I.U. and it is helping the depression noticeably. I have never taken this much but since I was at the bottom of the range it is helping tremendously and I can tell it has shifted but it will take time as I said for things to totally resolve.
I truly know how you feel if you would like to read my post it is titled "Waiting for the Miracle"
Wray will respond soon and there are answers right around the corner.
Hang in there and many Blessings,
Sage
Dec 09, 2012
 There is Hope
by: Wray

Hi Sage How wonderful of you to share your own experience with Catherine, we all need so much encouragement, as it's not an easy path. You are right, I did ask her to have a vitamin D test! I sound slightly manic about it, but after all the studies I've read, the stories I've heard about how it really does help, I can't but ask them to do a test. She is taking far too little too. I'm delighted you've noticed a difference by taking 20,000iu/day. I would so much prefer people to increase their levels of that, than keep going higher and higher with only the progesterone. For several reasons, the vitamin D is needed, no question about that, a lack reduces the benefits of progesterone, plus it's much cheaper than progesterone! So once it also begins to work, the progesterone can be reduced very slowly. Please keep in touch, I would love to hear how you get on. Take care Wray
Dec 09, 2012
 thank you all for your help
by: Anonymous

Thank you again for writing back with information.

I have still not received the natpro. I am glad that there is a Uk distributor. And also very glad to know about D-vitamin

Last time it was 35 n/mlo. I will follow the regime you written to me.

Although I am a little affraid of using more than 200 mg progesterone because I am so sensitive. But I will try to give it up to 500 mg.
In my post I also forgot to mention that I have chronique fatique syndrome and smoke much ( I have tried every possible thing to stop) but I have no will and is so stressed.
I will write back as soon as I begin the cream. God bless you all.
Dec 09, 2012
 Thank you all for your help
by: Anonymous

I am so glad for the help and info. I am waiting for the cream to come. I will write back as soon as I begin the cream and my D-vitamin is 35 nmol.

I also forgot that I have chronique fatigue syndrome. And smoke much (I have tried every possible way to stop) I cannot as I am stressed.

I am so happy for you help
Dec 09, 2012
 PLEASE HELP
by: Carol K

Hi there. I understand that you are in a very bad place right now, but hang in there and please take Wray's advice. You have come to the right place. She will help you. Besides the wonderful help you will get from using her Progesterone Cream, I was so pleased that she recommended EFT to you. This will definitely help you.I wish you all the best. Things WILL get better. Regards. Carol.
Dec 09, 2012
 thank you all for your help
by: Wray

Hi there Now I can understand why you are in such a state, I've rarely seen such a low vitamin D level!! It's severely low. You need to get your level up high very quickly, and I would suggest taking 100,000iu per day for 6 days only, then reduce down to 20,000iu as Sage is doing. Please contact Julienne who can give advice on it, she also holds stock too. Continue with the 20,000iu for 3 months, then have another test done. I would like to know the level then, so please come back to me with it. It could be you need to do the above protocol again. Don't be concerned about taking such a high dose, it is only for 6 days, levels up to 500,000iu have been given to elderly people in one dose, children given 100,000iu, I'm asking you to spread it over 6 days, see here, here, here, here and here. I took 100,000iu per day for a month, and it only raised my level from 85nmol/L to 197.5nmol/L, it's now 230nmol/L. Please don't forget to take magnesium with it, this is the most important co-factor for vitamin D. If you only take vitamin D and you have a magnesium deficiency, your pain could get worse. This is one of the signs you haven't enough magnesium. I've found the best is magnesium citrate or one chelated to an amino acid. It appears that CFS is caused by oxidative stress, I mentioned oxidative stress to you previously. There's also evidence depression is caused by it too. Oxidative stress leads to inflammation, see here. It could be gut dysbiosis causing it too, see here. Which fits in with your gut pain. You need to take about 4000mg/day inositol and 4000-8000mg/day glutamine. I didn't mention glutamine in my last reply, as I didn't know what the pain was caused by. Glutamine is essential for gut health, it's the only nutrient the enterocytes lining the gut wall can use for energy, repair and healing. And please consider taking a good probiotic too. Continued below
Dec 09, 2012
 thank you all for your help part 2
by: Wray

Hi there If interested we do have a Calming Complex, not on our website yet, but Julienne can get it for you. It contains all the calming amino acids, plus B vitamins, vitamin D and more, she can give the full details. It does contain a 4000mg/dose each of inositol and glutamine. Please have your mercury levels checked, particularly if you have many fillings, see here. This paper here is on vitamin D and fatigue. Don't worry about the smoking, giving up is stressful and the last thing you need is more stress. But please take as much vitamin C as you can, as smoking reduces levels quickly. The idea is to take it to bowel tolerance, i.e. before you get to the point of having a loose bowel. I do understand your concern about using high amounts of progesterone, but you found low amounts made you worse. It is best to start high, I think 400mg/day would be a good start. You might need more, Sage found she needed 1000mg/day, it's impossible to tell. Please read her page, you'll then see how she progressed up to that amount. Take care Wray
Dec 09, 2012
 PLEASE HELP
by: Wray

Hi Carol Bless you! Glad you also know about EFT, it's such a remarkable therapy. Take care Wray
Dec 09, 2012
 I will make a plan
by: catherine

Thank you all !!!

I have earlier taken so much magnesium that I was hospitalized. I cannot tolerate even small amounts of magnesium at the moment. Even foods containing magnesium give me bad bowel movement but I eat them.

Regarding D vitamin ok I will take the 6 days therapy I have found 35 ug at home per tablet, but I wonder how many of these I should take per day for six days? The test is a little diffecult to make in denmark as my doctor would only take it every three month because it is expensive.

I am glad you mention EFT in denmark it is called TFT and I do practice it when I am very stressed. My amount of B vitamin is very good as I have earlier taken huge amounts.

I will take c vitamin and hope for the best.

Now I have the best support so I can start the 400 mg cream with trust.

But a question to Wray:

Do you think I will be able to stop antacids one day?
Shall I stop the zoloft before taking the cream?
how long do you thing I shall be on 400 mg, just to order enough cream?

Thank you
Dec 11, 2012
 Please Wray answer me when you get time
by: Catherine

Hej again

I have taken 5000 IU vitamin D until today and again I got nausea and muscle pain and constipation. I have thought about your recommendation about magnesium. As I am very sensitive to oral magnesium. Would it help to use it as transdermal magnesium?

Please tell me if the feeling of collapsing all the time could be another sign of estrogen dominance?

And I will be happy if you also answer my other questions?

Good day
Dec 12, 2012
 I will make a plan
by: Wray

Hi Catherine Interesting about the magnesium, maybe it occurred because you're possibly short of vitamin D? Birmingham Hospital send out test kits for £30, about DKK278. They send the results back by email, but please ignore their 'adequate' level, far too low. Julienne has stock of the higher dose vitamin D, you would have to take about 71 tablets! The conversion is 40iu for every 1mcg. But it is important to have a test done first, before taking this amount. It could be I'm wrong and your vitamin D is fine. Although judging by your last test and the 1000iu you're taking I doubt it. I'm so pleased you practice TFT, it it slightly different to EFT, but works as well. In fact Gary Craig developed EFT from TFT. It's best to start the progesterone, vitamin D etc, before reducing the zoloft. We do have a page on Natural Antidepressants and how to wean off an AD. I wish I could answer your last question, it's one I'm always asked, and the answer is I don't know. What I do know is the worse the symptoms, the greater the number, plus the length of time they've been experienced, the longer it will take. But if you use sufficient progesterone, get your vitamin D level high, take vitamin B5, the anti-stress vitamin, and B3 which helps depression, the quicker it should be. If you use the 400mg/day progesterone, one tube will last 5 days. Take care Wray
Dec 12, 2012
 TO WRAY and Other helpfull ladies
by: Catherine

Hej Wray I hope you will help

I have still not received the cream yet and I have a period now.

I took around 5000 IU vitamin D for the last 3 days and got extreme muscle/joint pain , constipation so I took 350 mg magnesium yesterday and ended up having bad stomach, weakness and nausea. I could not sleep all night all night because of inomia and pain.

Today I did not take anything but I still have muscle pain. I feel weak and I am beginning to get a feeling that the progesterone cream will make me more bad.

I have a feeling of collapsing constant, please tell me it is because of estrogen dominance?

Please ladies I need your help and support
Dec 13, 2012
 Persaverance
by: Sage

Hello Catherine,
I know how hard it is right now. Please hang in there I am on day 25 of high progesterone doses 1000mg/day and a few supplements. Its so important to a large enough dose of progesterone to overcome the estrogen dominance symptoms.
I started with 250 then 550 then 600 and finally found some relief at 1000mg. I spread this throughout the day and in fact started with 100mg every hour or hour and half. Some symptoms are much better and the others are going to take a little longer. But like you it has been a very very long road and I had severe estrogen domaninace along with candidia and adrenal exhaustion and a few other things tied to this. When I started my Vit D I had strange and intense pain in my body then when I added the magnesium it all went away. I had a sensitivity to maganesium at one time due to toxic metals in my system and the magnesium would keep me up all night. The opposite of what it does for most people . . . . relaxation and many important functions. I no longer have this issue. Wtih all the stomach pain and need for antacids I would suspect a candida issue. Probiotics would be very helpful.
Antacids contain a high amount of aluminum and is more than likely contributing to your feeling so badly. Until the core problem is addressed which may be a combination of things some temporary things to do for your stomach could be peppermint tea,
peppermint essential oil on your stomach or Slippery Elm bark root powder mix in water - these all can aid in soothing the intestines temporarily.
Hopefully your cream will arrive today. I can't stress enough to start on a high enough dose. Wray is suggesting 400mg. Anything less is going to stimulate estrogen and make you feel worse. Please give it a try and stick with it.
I am here. Sending you lots of positive thoughts for health and well-being.

Blessings
Sage
Dec 14, 2012
 TO WRAY and Other helpfull ladies
by: Wray

Hi Catherine The muscle and joint pain from taking the vitamin D is caused by lack of magnesium. I wish you could have a vitamin D test done, as it would make things much clearer. It appears your level is very low, which would account for your symptoms, but without a test we won't know. You are very sensitive it seems, so I suggest you either persevere with the same amount of vitamin D and Mg, or reduce the amount of both and increase slowly. I feel you will get a similar reaction to the progesterone, as your oestrogen is probably high. Here again it's a question of working through the symptoms. But if you use sufficient progesterone it shouldn't be too bad. The feeling of collapsing is difficult for me to visualise, do you mean your muscles become weak? If this is so it indicates a lack of both Progesterone and Vitamin D. They both reverse myopathy or muscle weakness, but enough has to be used, see here, here and here. This last abstract has nothing on it, so I've pasted a passage from the paper... 'Substantial relief of myopathic disability by progesterone therapy'.....
(We report about a 41-year old woman who was suffering from a general muscle weakness since her early childhood....From July 1998 until July 1999 the patient was treated with progesterone suppositorium 0.4 g once a day from the 14th to the 25th day of the menstrual cycle. In July 1999 her gait had improved significantly and she could get up from a chair more easily, even her ability to walk up and down stairs had improved....Progesterone dosage was increased from 400 mg to 600 mg. In January 2001 the patient reported enthusiastically about the improvement she had gained from progesterone-therapy. The patient reported a clear increase in strength in all affected muscle groups resulting in dramatic functional improvement.) And these on vitamin D and myopathy here, here and here. Please make sure you use enough progesterone when it arrives. Take care Wray
Dec 15, 2012
 a question again
by: Catherine

I was about crying when I read your reply. Thank you for wanting to help.

I am now taking only 1400 IU of vitamin D only

I will take your advise and increase it gradually
I have ordered transdermal magnesium as we cannot have it here in Denmark.

I have lowered Zoloft to around 12,5 mg

I still take antacids and waiting for the progesterone cream.

I am drinking ginger for nausea
and taking colostrum powder for cleaning my system.

Regarding metal posining (two month ago I took much homopathy for cleaning my body that only made things worse)

As Wray says I am very sensitive

The feeling I have in my stomach is not acid, it is a feeling of a paralyzed stomach and as being pregnant.

Wray advised contacting Julienne for ordering the cream. Unfortunatelly She still has not replied and I am still waiting. If you know another place in the UK that can deliver quicklely at acceptable postage prices I will be happy.

MY BIG CONCERN NOW IS WHEN USING AT LEAST 400 MG PROGESTERONE is that it will make me weak, sleepy and anxious. I really need to start using it at high amount but I dont trust my body. A few calming words from you will be wonderful.

Another question I am on my 6 days of period. Shall I start right away when the cream comes all wait until the middle of the period time.

A big hug to all of you
Dec 15, 2012
 Persaverance
by: Wray

Hi Sage Bless you for making these suggestions, there's so much, too much to remember! The aluminium being but one, you are so right, they often contain it. I forgot to mention Candida to Catherine too. I'm most interested to hear you also had intense pain starting the vitamin D, and a magnesium sensitivity too. Thanks for the tips re the peppermint tea and oil, another thing I must remember. Take care Wray
Dec 16, 2012
 shall I start the cream
by: Anonymous

Hi agin I have now received the cream shall I start now I am on my 7 th day of period so it should be over or shall I wait until the middle of my period please advise
Dec 16, 2012
 Calming complex
by: Anonymous

Sorry for writing back to you. I am very interested in the calming complex please advise on purchase
Dec 17, 2012
 a question again
by: Wray

Hi Catherine Magnesium is absorbed well by the skin, but the cheapest form is magnesium sulphate. I buy 25kg from a farmer's co-op, maybe you could look for a farm supplier too. I throw 2-3 handfuls into my bath every night, a study showed it is absorbed, see here. I'm happy you've lowered the Zoloft, but please do it slowly. Another nutrient you could try for nausea is glutamine. This is remarkable at stopping nausea. It's the only substance the enterocytes lining the gut can use for energy, healing and growth. Plus the brain can use it in place of glucose for energy, so if blood glucose is a problem, it helps stabilise it. I can only imagine the reaction you had to the homeopathic meds was from a detox reaction, it would make things worse. This shows you must have heavy metals. Another nutrient you could consider is NAC (N-acetyl cysteine), this chelates heavy metals and a few other toxins, see here, here and here. If you don't have an acid stomach, I think you should stop the antacids, as Sage says some have toxic substances in them. The 'paralysed' stomach sounds like myopathy again, I would hope this goes once your vitamin D and progesterone levels increase. Oestrogen also constricts smooth muscle which is found in the gut, so it could be caused by an excess of this too. I do know Julienne has replied to you, she told me so. But said she was waiting for your reply. Maybe her email has gone into your junk box, please have a look for it there. I have found 400mg/day is a good starting point. But as you saw from Sage's comments, she had to take it much higher before it began helping. If you could begin taking those natural antidepressants too, I'm sure these will help. I feel with the symptoms you have you'll need to use the progesterone daily, ignoring any cycle. So you can start it as soon as you get it. It's far more important to get rid of symptoms first, than bother about when you bleed. This might continue to occur, in some women it stops. This is nothing to worry about, in fact there's reason to believe we all bleed far too often. Up until the industrial revolution women had about 100 periods in a lifetime, now we have over 400, see here. This is another worth reading, see here. Take care Wray
Dec 17, 2012
 Very thankful to you and Sage and Julienne
by: catherine

Thank you very much for your reply. All the information is great and useful. Yes Julienne was so kind to reply and I am so happy for that. She is indeed a kind person and seems so passionate when relying.

I will start the cream tomorrow morning and try to up my d vitamin with support from Julienne. About the Glutamine I hope julianne will be able to send me the calming complex as you said there is Glutamine in it.

I just want to make a warning regarding rosemary and lavender, I think they both stimulates estrogen as I almost cry when I drink the the tea and begin to sweat.

To my surprise I called the doctor today and my last measurement of D vitamin was 26 nmol so no wonder I am in pain.Again thank you for your help I will follow up with Julienne and write with hopefully better health.
Dec 19, 2012
 I hope I can hang on here
by: catherine

Dear Wray I hope I still can get advise on this site. Regarding help from Julienne I feel I am pressing her and I dont want to feel this way so I will keep hanging on here as long I am using your cream.

My first what is the name of the calming complex so I can order it?

This is my second day of progesterone and honestly I feel awful. I am about to cry every moment.

I dont know if it os normal or I should lower it down from 400 mg.

The problem with a feeling of collapsing is a little better but my body feels as a jello shaking with no strength. I appreciate your reply for comforting and advise.
catherine
Dec 19, 2012
 Very thankful to you and Sage and Julienne
by: Wray

Hi Catherine Start the cream as soon as you wish, it doesn't matter if it upsets the cycle, you need to get rid of symptoms first. Please use it daily, through any bleeding too, for at least 2-3 months, it could take longer. I've organised for the lab to send some calming complex to Julienne. She can then send it over to you whenever you need it. You are sensitive to many things, so I think you should avoid the herbal teas. Thank you for finding out your vitamin D level, it's terribly low. I'm shocked the doctor didn't do anything about it. Do keep in touch with Jules or me. Take care Wray
Dec 19, 2012
 wait for calming complex
by: catherine

good evening I am about convincing my doctor to give me 100000 iu d vitamin injections.

I tried to get off antacids for one day but I could´t which here I blame the progesterone cream as I normally can go off it one day.

I will hang on until this has subsided and the cream begins to work.

My biggist concern is ringing in my ears and shaking. I hope it is just a phase. Or maybe it is because I took 5000 IU d vitamin today.

As I wrote to Julienne I will be happy if you tell me when she gets the calming complex.

I am using 189 mg of transdermal magnesium so I hope it is enough.
catherine

catherine
Dec 20, 2012
 I hope I can hang on here
by: Wray

Hi Catherine Julienne is quite happy to give you advice, but she does have a full time practice doing EFT. So there will be times when she won't be able to respond as soon as you would like. The same with this site, there is only me to answer all the queries that come in. The name of the complex is the Calming Complex. I have organised for the lab to send stock over to Julienne for you. But as it's Christmas, the post will be very much slower than normal. Yes it is normal and I did warn you that symptoms could be bad when first starting it. I also gave you our page on Oestrogen Dominance which explains why it occurs. Are you using 400mg/day, it's 12ml of cream? But it's evident you need more than this, can you increase it? Please read Sage's advice on the 13th Dec, she has had to increase substantially, which is slowly beginning to work. There are countless other women who have written in to the site saying they had to use a great deal, as their symptoms were so bad. These are a few comments here and here. Once you get your vitamin D level up it should help too. You need to do this quickly, the capsules you have are far too weak to do this. Julienne can help you with the vitamin D too. The muscle weakness will go, I gave you those papers, plus the paste of the one paper, on the 14th Dec. If they had given the one patient more than the 400mg/day she would have recovered far quicker. It wasn't until a year later they gave her 600mg/day and then she had a dramatic improvement, but it still took 6 months. So it's evident you need more than the 400mg, but you have only used it for 2 days. As you can see from the paper it can take months. I know it will eventually help you, but it does require time and patience. Take care Wray
Dec 21, 2012
 wait for calming complex
by: Wray

Hi Catherine That is good news if you can get such a high dose of vitamin D! That will really boost your levels, but you must continue taking it too. A once off ultra high dose starts wearing off after a month, and you're back to square one. I don't think progesterone is to blame for the antacid problem, more likely oestrogen as it's an inflammatory hormone. Progesterone helps inflammation in the gut, see here and here. It's always best to boost your body with the nutrients it needs, before attempting to reduce any medication. I'm sure the ringing and shaking is a phase, and will pass. It could have been the vitamin D, it's so difficult to tell, as you're very sensitive to everything. This will also pass too, once you become stable. We will let you know when the CC arrives at Julienne. If you feel you can handle the 189mg magnesium then that's wonderful, no need to rush things. Take care Wray
Jan 07, 2013
 hi
by: Catherine

Hi everyone

I am writing to you as I have had severe psymptoms while on 400 mg cream. Most of all a nervous break down and low blood sugar, extreme heart race. Well I am not blaming the cream but must admit that I am too sensitive to any hormone.

Wray: If you know anybody who could use three unopened tubes of the cream at good price please tell me as I want to sell them again.

thank you
Jan 09, 2013
 hi
by: Wray

Hi Catherine I wish you'd either contacted me or Julienne about this. It's evident you are responding to the progesterone, but your oestrogen is so high it's still being stimulated by the progesterone. You really need to go far higher to help. Sage gave you advice, as you can see she didn't stick with the 400mg/day, that is only a guide line for starting if symptoms are severe. Oestrogen causes blood glucose to drop, progesterone stabilises it, see here. Oestrogen causes prolongation of the QT interval, which results in palpitations, arrhythmia, Torsades de Pointes and sudden death. Whereas progesterone shortens the QT interval, see here, here, here, here, here, here and here. Oestrogen stimulates glutamate, our most excitatory neurotransmitter, see here. An excess of glutamate will cause anyone to spin out, with hectic moods etc. Oestrogen increases free radicals, plus destroying beta-endorphin neurons in the brain, these produce endorphins which promote a feeling of well being and relaxation. Beta-endorphins also appear to boost the immune system, protecting against cancer, see here. This paper says "Although it is widely accepted that exposure to estradiol throughout life contributes to reproductive aging.... Recent evidence ..... of chronic estradiol-mediated accelerated reproductive senescence now suggests such a hypothesis. It has been shown that chronic estradiol exposure results in the destruction of greater than 60% of all beta-endorphin neurons in the arcuate nucleus .....This loss of opioid neurons is prevented by treatment with antioxidants indicating that it results from estradiol-induced formation of free radicals", see here. Continued below
Jan 09, 2013
 hi Part 2
by: Wray

Hi Catherine Whereas progesterone protects against glutamate toxicity, it also increases BDNF (brain-derived neuroptrophic factor) in itself protective, see here and here. It's essential to use enough progesterone to overcome the high oestrogen. There is nothing else that will get it under control, other than progesterone. Unless you go on a drug like lupron, which of course comes with adverse side effects, apart from stopping ovulation too. Which means no ovarian progesterone will be made, which is not what you need. Please would you get your glutamate levels checked, your progesterone to oestrogen ratio too. Keep taking the vitamin D and get that up as fast as you can. Please send the tubes back to Julienne, maybe you could send an email to her for her postal address, I don't want to give it here on the web. Then please send us an email via this form here, asking for a refund. We will need your details too. Take care Wray
Jan 14, 2013
 sent my information
by: catherine

Hej Wray

I have now sent you detail about the three tubes and I hope you write back to me
Jan 15, 2013
 sent my information
by: Wray

Hi Catherine Many thanks, I'll check for it. Did you send an email to Julienne asking for her address details? I'm sorry the further info I gave you didn't make you realise how much you do need progesterone. Take care Wray
Jan 15, 2013
 hi
by: catherine

no unfortunately I did not contact Julienne but sent you all the information, did not realize I should contact her?

Unfortunately My anexiety and stomach acid has increased so much that I cannot function anymore after using the cream I cannot keep on it as I now feel anxiety about everything. I really would like to pass the cream to someone who could benefit from it. So I appreciate your help
Jan 16, 2013
 Possibly Reconsider
by: Sage

Catherine, this is Sage who posted replies previously. I write this post now not to try to convince you to use progesterone but to share my own experience and hopefully help you to see the situation differently.

First of all I will tell you when I started the “high dose” progesterone therapy I was very leary. I had tried to use progesterone off and on in the past 10 years with little success and so believed it really was not the issue I was dealing with. I had used 100-200mg of progesterone with little success. And I always ended up not feeling ‘good’ like everyone else claimed this was their panacea. Why wasn’t it mine?

In November of this last year (2012) is when I so to speak ‘bit the bullet’ and tried the higher doses. I was scared to death to do so because I had experienced a definite intesification of symptoms including anxiety, depression and a feeling of being so toxic.
At this point I thought to myself what do i have to loose, I feel so bad already and have lost all hope - what is the worst thing that could happen? More of same which I always lived through before. And the amazing thing is that once I made the decision I now understood what had been happening off and on for 10 years. By the way I am 45 and have had hormone and many other problems since 30 and even my teens. I am clearly aware of what anxiety means. I had to drop out of high school and do at home education do to such bad anxiety.

The higher dose which first tried at 250mg then 500mg then 600mg and then had a tragic loss right when I was trying to find some relief I went up to 1000mg. This really did help. In all honesty it did not relieve everything and some things were intensified due to the stimulation of estrogen. But it was still better than where I was prior to the higher doses and it keeps getting better. It has now been 9 weeks at a steady 1000mg/day in divided doses and measured exactly with a 1/2 tsp and 1 tsp. I can feel myself coming back on again. And this is wonderful but coming from where I came from just to be out of intense emotional/mental suffering most of time is a tremendous accomplishment.

The biggest idea I need to convey is that I had to get past my prior experience of taking a larger dose of progesterone. It is very scary when the very thing you are anticipating is going to make you feel better (to say the least - more like calm down anguish) intensifies the exact problem you were trying to relieve. It really does mean taking a large enough amount. I did not wait long in between titrating upward it was only 5 or 6 days before I went up to 1000mg.
Jan 16, 2013
 Continued "Reconsider"
by: Sage

And as time goes on and my Vit D levels are increasing which were bottom of range and a few other things are addressed my health is MARKEDLY improved especially mental and emotional and of course physical.

There are other factor to consider along with the estrogen dominance such as adrenal exhaustion, copper toxicity, candida and side effects from anti-depressants or anti-anxietals. These conditions can make it seem like the progesterone is NOT working but I assure you it is and just sticking with it and one step at a time dealing with the other things and deciding what needs to be done, it truly does all come together and begins to bring noticeable relief and give assurance you are on the right path.

If you did decrease the Zoloft this is definitely playing a large role in symptoms including nervous breakdown. I need to add here that there are ways to ‘safely’ get off these medications and feel better than before the need to even go on them was necessary.
There is more information here that I can not elaborate on this website. But could be extremely helpful in regaining a sense of well-being.

Addressing estrogen dominance is in my opinion absolutely essential to regaining an experience of Joy in one’s life much less the alleviation of symptoms. 


My hope is that you will re consider and just start taking 1000mg/day and see what happens. You can always just stop again but it is worth the chance to prove to yourself through your own experience.

Many Blessings
Sage
Jan 18, 2013
 hi
by: Wray

Hi Catherine Yes I did ask you to email her for her address, so that you could send the cream back to her, rather than back to the States. As I've said previously, the 400mg/day is only a suggestion, it was evident the way you reacted that your oestrogen is very high, so you would need far more, pity you won't continue. I can't think of anything else that will help. Take care Wray
Jan 18, 2013
 thanks
by: Catherine

Thank you Sage for sharing your story with me. I am sorry to tell you that I cannot afford a 1000 mg per day at the moment. Also I have learned that my body cannot have any hormones. I have tried with all congenital hormones and progesterone and I will be frightened to go up. Obviousely I get the opposite reaction of every thing I take.

I have eleminated Candida and taking colostrum should have dealt with adrenal exhaustion.
Right now I want to get on track again going back to antidepressants. I am not ready for the hormone fight yet. Maybe in a couple of years but right now my little children needs me.

Wray: I have received Juliennes adress and will send it to her tomorrow. please let me know when everything is ok
and again thank you for your help
Jan 23, 2013
 Possibly Reconsider
by: Wray

Hi Sage Bless you for encouraging Catherine, but it seems she's not in a position to increase the amount, mores the pity. I'm so happy you're now finding relief at last! Take care Wray
Jan 23, 2013
 thanks
by: Wray

Hi Catherine It's such a pity you can't afford to use 1000mg/day, it's helped so many, Sage included. Our body runs on hormones, a lack causing severe symptoms, exactly as you are experiencing now. The 'opposite' reaction you get is only oestrogen dominance, which occurs in many, many women. Thanks for sending Julienne the cream, she says she's received it. I do hope you've been reimbursed, if not let me know and I'll send another note to remind that department. Take care Wray
Jan 25, 2013
 thanks
by: caherine

Thank you Wray but I cannot run the hormone fight right now

please tell me how I will be receiving payment for the cream

again thank you
Jan 27, 2013
 thanks
by: Wray

Hi Catherine We normally refund via Paypal, so hopefully you gave your details on the form I asked you to fill in. I do understand your predicament, having three young children to take care of is a full time job. It's a pity you can't get someone to look after them while you heal. I did that for a friend of mine once, she came to stay for 10 days, while her husband looked after the children for her. Take care Wray
Jan 27, 2013
 thanks
by: catherine

Thank you Wray I have resent the form with paypal address

I wish I lived under other circumstances and could fight depression and anxiety in another way. I certainly would consider the therapy when I am strong enough to do so but right now I want to get rid of my nervous break down and get my mind on track again

All respect to you ladies
Jan 28, 2013
 thanks
by: Wray

Hi Catherine Many thanks, I'll follow up my end. I also wish you did, but if you ever need any of us, please write in. Take care Wray PS I see the department has been in contact with you, I hope you get the refund soon.
Feb 02, 2013
 thanks
by: catherine

Dear Wray thank you I will get back to you in case I need help. Have not been able to reply you before now.

I have still not received any payment for cream and asked the department to contact you in case there is any problem as they asked me to provide postage proof and I dont have it but Julienne has already received them. Take care
Feb 03, 2013
 thanks
by: Wray

Hi Catherine I'm so sorry about this, as I did tell that department you had sent Julienne the cream and that she had received it. I have reminded them of this fact again today. I will chase it up again on Monday. I do hope one day you'll have the time to consider using the nutrients to heal. We will always be here to help you. Take care Wray
Feb 05, 2013
 thanks
by: Wray

Hi Catherine I've spoken to our department who handles refunds. And they didn't ask for proof of postage. But asked you for the details of your original order, as they cannot find your order at all. Do you know who you bought it from? Take care Wray
Oct 14, 2013
 toxic!!
by: Anonymous

you sound like to me that your liver may be toxic! I believe I am having this issue too, but not near as severe as you are! Bless you!! I am so sorry you are going through this!! I am researching now ways to detox my body, especially my liver. One of the things that has helped me, along with taking high doses of progesterone cream is a supplement called DIM Plus. It comes from crucifious vegetables such as broccoli and leafy greens and it helps your liver metabolize excess estrogens...the bad ones that cause cancer. I only took it for about a week and it cured my migraines...which i had started having. I also added magnesium and calcium together, before bedtime, it helps the progesterone to work better. I will be praying for you. God is there with you, call on Him in your times of distress and make him your fortress, he wants to help you.

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