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Please help my understanding.

by Natalie

Please could anyone help me? I've been using 3% progesterone cream since January. My doctor told me to start low, so I did, but I kept feeling worse. I've upped it each month and, am now at 250mg cream.

Each month I have had different weird and awful symptoms. Each month I have battled through and put this down to the 'worse before better' phenomenon.

It has been a truely awful experience, and indeed, for the most part, feels like my estrogenic symptoms are always sky high.

I now intend to stay at 250mg and try and balance.

Can someone please explain to me what is actually happening scientifically when I up my dose and get worse??? Im beginning to think it's a bit far fetched and maybe progesterone itself is the cause of my problems. This has gone on so long. I've actually been worse since starting progesterone.

If you think sticking at 250mg consistency for 3 months or so will solve it, I'll do it. But I cant cope with another 3 months feeling so vile. Neither do I wavt yo change my dose, again as it always makes, me worse.

Can anyone advise?

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Sep 07, 2022
 Please help my understanding
by: Joy

Hi Natalia

I'm sure I addressed this or something similar in July or perhaps I have the wrong person. Your post now sounds so familiar.

I really wish that doctors would read the research papers. Nothing less than 100mg is needed. That would explain why you felt worse. Usually between 100-200mg is required, more if symptoms are severe. It can take anything from 2-6 months before benefits are felt provided progesterone is used correctly and Vitamin D3 level is optimal. Do you know what your level is? The How to use Progesterone Cream explains in more detail. I suggest that you stay on 250mg until you feel stable, then and only then, slowly reduce to a level that suits you. Use half the amount in the morning and the other half at night. Did your doctors tell you this? This will keep progesterone levels stable, otherwise it will spike. Your body needs to adjust to the new amount, once progesterone is dominant, you will feel much better.

The small dose advised by your doctor aggravated your estrogen receptors and that is not what any woman needs. It would have made your Estrogen Dominance even worse.

Progesterone therapy is not easy, I wish it was. Time and patience is required. It can get very confusing with so much misinformation given on the internet today, mostly by uninformed people.

Good luck.

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