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Need advice on use of Progesterone Cream

by Maz
(Brisbane, Australia)

Hello Wray

I have been using the Progesterone Cream now for about 7 - 8 weeks. (I might add here that I have just finished chemo therapy and radiation for breast cancer). In any case I have been using the cream now twice a day on breasts, wrists, elbow crease, behind knees, under arms, neck and after only 7 weeks my cycle returned which I am grateful for as doctors said that they did not believe they would because of my age and the chemotherapy.

Anyway, I want to know can I still use the product every day, twice a day, from here on in or do I have to have the advised 14 days on and 14 days off. I am of the understanding that you cannot give yourself too much and I actually have a feeling of comfort knowing that I use it each day in the aid of warding off any possible breast cancer or other cancer in the future.

Can you please advise what I should do.

Kind regards

Maz Franz

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Dec 07, 2007
 When to use progesterone
by: Wray

Hi Maz. Thanks again for sharing your story! Strictly speaking you should be using the cream following your cycle now that it's come back. If you don't it will disrupt it. I feel though, due to the circumstances, it would be a good idea for the next few months to ignore your cycle and use it every day. When you feel confident and the scar has healed fully, then you could think about following it. By using it every day you will suppress any excess oestrogen you still have.

Incidentally it shouldn't be used 14 days on, 14 days off. Our cycles can vary from as little as twenty one days to as long as thirty six. The average being twenty eight days. This is the reason that the manufacturers of The Pill and HRT pack their product in twenty eight day cycles.

To give you some idea, all women, irrespective of the length of their cycle, should start ovulating fourteen days before they start bleeding again*. So start using the cream either at ovulation, if you know when it happens, or fourteen days before your next period is due.

*NB
A twenty one day cycle Ovulation should occur on day seven
A twenty eight day cycle Ovulation should occur on day fourteen
A thirty six day cycle Ovulation should occur on day twenty one

As for dose, too many 'authorities' tell us to use only 20mg/day. If there is a severe problem, this amount won't touch sides! Dr Dalton, who to my mind was the world's foremost authority on progesterone before she died, would use up to 2400mg/day for patients with post natal psychosis.

All the successful studies done on progesterone used between 100-200mg/day, this equates to 3-6ml/day of Natpro. I vary my dose between these two figures and have done so for 12 years now. (Some studies have gone as high as 400-600mg/day). When stressed I put more on, as progesterone drops when stress hormones are released. They have also found progesterone reduces the reaction to stress as it activates the GABA receptor sites. GABA is the main calming neurotransmitter. Adrenaline is one of the hormones produced in response to stress, it has been found to prevent cancer cells from dying.

Brain Res (2005) 1043: 76-86.
Progesterone regulation of catecholamine secretion from chromaffin cells.
http://www.ionchannels.org/showabstract.php?pmid=15862520

Emory University Health Sciences Center
Article Date: 09 Feb 2005 - 8:00 PST
Sex hormone metabolite reduces stress, anxiety in female rats
http://www.medicalnewstoday.com/medicalnews.php?newsid=19777

J. Biol. Chem, 10.1074/jbc.M611370200
Submitted on December 12, 2006 Accepted on March 12, 2007
Epinephrine protects cancer cells from apoptosis via activation of PKA and BAD phosphorylation
http://www.jbc.org/cgi/content/abstract/M611370200v1

Do hope this helps! Take care Wray
Dec 07, 2007
 Use of Progesterone Cream
by: Maz

Thanks Wray for your information regarding use of cream after return of cycle.

I will be using the cream daily and I intend now to increase the amount that I have been using.

I only today visited the radiologist oncologist and we spoke regarding use of Tamoxifen and she advised me to use it especially if I really wanted to get the most life possible.

Apart from what science has studied she couldn't comment on "progesterone cream" as she said she did not know. My own personal experiences say this cream is sensational.

I do not intend to take Tamoxifen especially now that my cycle has returned even though they now say that I am at a higher risk of cancer returning as I now most definitely produce more oestrogen and so I am more susceptible to cancer elsewhere.

I personally choose not to go this line of thinking. I use progesterone cream every day, in fact twice daily and I am using other alternative therapies to compliment this and to gain positive results.

I am very happy where I am in amongst all of this. I am taking control and I am not allowing myself to be a "guinea pig" in all of this.

Here's to a long life, happy life, full of meaning life, enjoying the simple life, laughing lots and spreading good cheer wherever I go.

Life is short and death is for a long time, so don't lose sight of your life right now. Enjoy. Love Maz.
Dec 09, 2007
 Use of Progesterone Cream
by: Wray

Hi Maz. My heart missed a beat when you said you'd been advised to go on Tamoxifen, until I read further down! Tamoxifen will not give you the 'most out of life'. It used to be given for five years, now it's been reduced to three, due to an increased risk of getting cancer! The NIH Medline info has this to say:

Tamoxifen, IMPORTANT WARNING: Tamoxifen may cause cancer of the uterus (womb), strokes, and blood clots in the lungs. These conditions may be serious or fatal. Tell your doctor if you have ever had a blood clot in the lungs or legs, a stroke, or a heart attack. http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a68
2414.html

By counteracting the oestrogen you will be making by using progesterone I feel confident you will be protected. And as the paper I gave you stated, a high adrenaline level in the system keeps cancer cells alive.

By following a fear based system, ie Tamoxifen, you will keep adrenaline high. By following the system you have chosen it will be low. So here's to a long and happy life! Take care Love Wray

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