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Ingredients

by Karen Loudon
(Placentia, CA USA)

Is the source of the soy you use to manufacture the progesterone from organic, non gmo soy?

Also, you state non synthetic antioxidants. dl-alpha tocopherol is synthetic. dl indicates synthetic and d-alpha is natural. Can you explain?

Thank you.

Comments for Ingredients

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Jul 07, 2011
 Soy information?
by: Anonymous

Where does it tell that the source of the progesterone is soy? I would like to see this information.
Jul 08, 2011
 Ingredients
by: Wray

Hi Karen We don't use soy progesterone anymore, as it was causing too much confusion with customers. We now get it from a yam source. I can't find where we have stated we use non synthetic antioxidants. dl-alpha tocopherol is synthetic. It's used in concentrations of 0.05 to 0.2% in cosmetics as an in vitro antioxidant. The natural form, d-alpha tocopherol is an in vivo antidoxidant, and cannot be used as an in vitro one. We do have more info on the ingredients in the cream, see here. Take care Wray
Jul 10, 2011
 Yams
by: Anonymous

In the ingredients section you state that, "none are bogus "Yam Creams." But now your cream is made from yams. Can you explain? Is it ok to use cream made from yams? Sorry for my naivete but I dont udnerstand. Thanks.
Jul 14, 2011
 Yams
by: Wray

Hi there I don't where where you found the reference to "none are bogus "Yam Creams." Many people are confused about how progesterone is made and where from. The confusion arises as so many web sites say made from yam, while others say made from soy. Interestingly, none of the pharmaceutical firms making progesterone injections or suppositories for use in IVF treatments, miscarriages or pre-term births, mention where the progesterone comes from. Which is the best or safest is always upper most in people's minds. The bottom line is it doesn't matter what plant is used for synthesising progesterone, providing it contains a plant sterol in sufficient quantities to make it economical. All plants have sterols, often called phytosterols.  Animals only have one sterol, more commonly known as a zoosterol, which we call cholesterol, and fungi only have one called ergosterol. They are an integral part of cell membranes and precursors to many things, for instance in animals to hormones.  But there are plant sterols and plant sterols. The phytosterols used for making progesterone do not have a triple bond in the A-ring as oestrogen and the phytoestrogens do. In fact they have no bond in the A-ring, unlike progesterone which has one.  So the molecule must be changed, this has to be done in a lab. For instance the conversion of stigmasterol to progesterone takes place over 11 reactions, each producing a different molecule. Until the final step produces progesterone. Cholesterol is the starting point for the steroid hormones made naturally in animals, including humans. But it's expensive to use for the manufacture of progesterone, so plant sterols are used instead. Plants such as the soy bean, Dioscorea species of yams, fenugreek, sisal, calabar bean, some lilies, yucca, some solanum species, maize and many more contain phytosterols. Some of which are stigmasterol, diosgenin, beta-sitosterol, campesterol, hecogenin, sarsasapogenin, solasodine. As these plant sterols have a similar molecular structure to cholesterol, they are used as starting points for the synthesis of progesterone. So the synthesis ends with a progesterone molecule, or molecules, as it's made in large quantities. It is only progesterone and can only be progesterone. Take care Wray

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