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increase dose or take a break?

by Louise
(England, UK)

Thank you so much for all the info on this site! It's literally been a Godsend. I'm 49, perimenopausal, started using Progesta 10% cream 6 months ago in order to address insomnia, anxiety, hot flashes, low mood and sore muscles. After a few months of adjustment it was working like a dream. As periods have been very heavy, long and painful for me, I have used the cream continuously for the past three months. I use the pump dosage, which seems to be 1/4 teaspoon, in the morning and on going to bed. According to the packaging this equates to two 125mg doses....However, for the past month my breasts have been extremely sore. I feel like I have PMS again. Although my other symptoms are more or less ok, I'm wondering if I need to increase the dose? Or, should I have a bleed? I am concerned that the womb lining is building up......

I think I may have triggered the problem by attempting to reduce my dose. There were supply issues with Progesta here in the UK and I tried to wean myself off having so much. However this was literally only for two or three days, max.

Please can you give me your advice? With warmest wishes, Louise x

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May 11, 2022
 increase dose or take a break?
by: Joy

​Hi Louise

Personally I am not in favour of the 10% creams. It also confuses many people. Information on this website is based on Natpro which is a 3% cream and was formulated nearly 30 years ago. If you are going to continue to use the 10% cream please adjust the amount used so that it equates to that of Natpro. Natpro delivers 50mg per pump.

Tender breast could indicate that you are still battling with Estrogen Dominance or your iodine, selenium and tyrosine levels are low. Have these been tested and well as your thyroid? Try rubbing some progesterone cream on your tender breast it should help as it is an excellent anti-inflammatory.

Usually between 100-200mg (3% cream) is needed per day with no breaks as you are in Peri-Menopause. More may be needed if symptoms are severe. Please read the How to use Progesterone Cream page.

Did anyone at Progesta inform you about Vitamin D3 and it's importance? A deficiency reduces the benefits of progesterone and is connected to every single functioning cell in our bodies including the thyroid​​.

Take care.

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