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Epilepsy treatment references



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Phase III Progesterone Therapy Trial For Women With Epilepsy Has Favorable Outcome

Female reproductive steroids and neuronal excitability

Curr Neurol Neurosci Rep. 2011 Aug;11(4):435-42
Hormonal therapy for epilepsy

Arch Gynecol Obstet. 2011 Sep;284(3):749-55
Epilepsy and menopause

Neurol India. 2011 Jan-Feb;59(1):59-65
Managing epilepsy in pregnancy

Seizure. 2011 May 23
No effects of the gonadal hormones on photoparoxysmal EEG responses in idiopathic generalised epilepsy

Med Hypotheses. 2011 May;76(5):661-4
Light therapy as a treatment for epilepsy

Intern Med. 2011;50(11):1235-7
Reading epilepsy as the initial symptom of idiopathic hypoparathyroidism

Medscape October 12, 2010
Infertility Risk Higher for Women With Epilepsy

Pediatr Neurol. 2010 Nov;43(5):320-4
Effect of carbamazepine therapy on vitamin D and parathormone in epileptic children

Neuropharmacology. 2010 Dec;59(7-8):573-8
Disease-modifying activity of progesterone in the hippocampus kindling model of epileptogenesis

Neuroscience. 2010 Oct 27;170(3):865-80
Neurosteroid withdrawal regulates GABA-A receptor 4-subunit expression and seizure susceptibility by activation of progesterone receptor-independent early growth response factor-3 pathway

Gynecol Endocrinol. 2010 Nov;26(11):783-90
Catamenial epilepsy: hormonal aspects

Best Pract Res Clin Obstet Gynaecol. 2010 Oct;24(5):593-604
Contraceptive options for women in selected circumstances

Med Hypotheses. 2010 Jan;74(1):158-61.
Benefits of sunlight: vitamin D deficiency might increase the risk of sudden unexpected death in epilepsy

Clin Neurol Neurosurg. 2010 Jan;112(1):1-10. Epub 2009 Nov 12
Bone and calcium metabolism and antiepileptic drugs

Psychoneuroendocrinology. 2009 Dec;34 Suppl 1:S265-77
Vitamin D, a neuro-immunomodulator: implications for neurodegenerative and autoimmune diseases

Neurotherapeutics. 2009 Apr;6(2):392-401
Neurosteroid replacement therapy for catamenial epilepsy

Epilepsy Res. 2009 Sep;86(1):42-7
Non-alcoholic fatty liver disease (NAFLD), insulin resistance and lipid profile in antiepileptic drug treatment

Seizure. 2008 March; 17(2): 176180
Hormone Replacement Therapy: Will it affect seizure control and AED levels?

Int Rev Neurobiol. 2008;83:385-95
Issues for mature women with epilepsy

Epilepsia. 2008 Sep;49(9):1619-26
Reproductive hormonal changes and catamenial pattern in adolescent females with epilepsy

Seizure. 2008 Mar;17(2):172-5
Does menopause affect the epilepsy?

EJE Volume 17, Issue 2, Pages 151-159 (March 2008)
Catamenial epilepsy: Definition, prevalence pathophysiology and treatment

Neurosci Lett. 2007 Jan 10;411(2):147-51
The anticonvulsant effects of allopregnanolone against amygdala-kindled seizures in female rats

Altern Med Rev. 2007 Mar;12(1):9-24
Natural approaches to epilepsy

Epilepsia. 2007 Jan;48(1):66-71
Vitamin D status in children with intractable epilepsy, and impact of the ketogenic diet

Nutr J. 2007 Sep 19;6:23
Maternal vitamin D deficiency associated with neonatal hypocalcaemic convulsions

Neuroscience Letters Volume 394, Issue 1, 6 February 2006, Pages 69-73
Increased severity of chemically induced seizures in mice with partially deleted Vitamin D receptor gene

Epilepsia. 2006 Mar;47(3):510-5
Vitamin D levels and bone turnover in epilepsy patients taking carbamazepine or oxcarbazepine

Brain Res. 2006 Jul 26;1101(1):110-6
The anticonvulsant effects of progesterone and its metabolites on amygdala-kindled seizures in male rats

Epilepsia Volume 47, Issue 9, pages 14231440, September 2006
The Influence of Gonadal Hormones on Neuronal Excitability, Seizures, and Epilepsy in the Female


The American Society for Nutritional Sciences J. Nutr. 135:279-282, February 2005

Vitamin D Deficiency in Early Infancy

Brain Research Bulletin Volume 67, Issues 1-2, 30 September 2005, Pages 156-160
Anticonvulsant effects of 1,25-dihydroxyvitamin D in chemically induced seizures in mice


Arq. Neuro-Psiquiatr. vol.62 no.4 So Paulo Dec. 2004

Bone mineral density and serum levels of 25 OH vitamin D in chronic users of antiepileptic drugs

Medscape Neurology & Neurosurgery 6(1), 2004
Menstrual-Related Seizures and Psychosis

Annals of Neurology 2003, Volume 53, Issue 3 , Pages 390 - 391
Seizure exacerbation associated with inhibition of progesterone metabolism

Trends Endocrinol Metab. 2002 Apr;13(3):100-5
New clues about vitamin D functions in the nervous system

Epilepsia Volume 42 Issue 2 Page 216 - February 2001
Circulating Levels of Allopregnanolone, an Anticonvulsant Metabolite of Progesterone, in Women with Partial Epilepsy in the Postcritical Phase

Psychoneuroendocrinology. 2000 May;25(4):407-20
Anti-seizure effects of progesterone and 3alpha, 5alpha-THP in kainic acid and perforant pathway models of epilepsy

Epilepsy Volume 40, Issue 10, pages 14021407, October 1999
The Effect of Menopause and Perimenopause on the Course of Epilepsy

THE JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS Vol. 288, Issue 2, 679-684, February 1999
Finasteride, a 5a-Reductase Inhibitor, Blocks the Anticonvulsant Activity of Progesterone in Mice

Epilepsy Res. 1998 May;30(3):195-202
Evaluation of the anticonvulsant profile of progesterone in male amygdala-kindled rats

Epilepsia Volume 38 Issue 10 Page 1082 - October 1997
Three Patterns of Catamenial Epilepsy

J Endocrinol Invest. 1997 Oct;20(9):519-26
Menstrual cycle and ovary alterations in women with epilepsy on antiepileptic therapy

Neurology. 1996 Nov;47(5):1264-8
Treatment of four siblings with progressive myoclonus epilepsy of the Unverricht-Lundborg type with N-acetylcysteine

Brain Res. 1995 Oct 23;696(1-2):113-20
The neurosteroid 3 alpha, 5 apha-THP has antiseizure and possible neuroprotective effects in an animal model of epilepsy

Epilepsia. 1995 Apr;36(4):355-9
Ovulatory function in epilepsy

Epilepsy Res. 1989 Mar-Apr;3(2):100-6
Unbalanced progesterone and estradiol secretion in catamenial epilepsy

Acta Physiologica Scandinavica Volume 131, Issue 1, pages 33 42, September 1987
The effect of progesterone and its metabolites on the interictal epileptiform discharge in the cat's cerebral cortex

Q J Med 1986; 59: 569-577
A Comparative Study of the Relative Influence of Different Anticonvulsant Drugs, UV Exposure and Diet on Vitamin D and Calcium Metabolism in Out-Patients with Epilepsy

Acta Neurol Scand. 1976 Oct;54(4):321-47
Epileptic seizures in women related to plasma estrogen and progesterone during the menstrual cycle

Br Med J 1974;2:258-259 (4 May)
"Anticonvulsant Action" of Vitamin D in Epileptic Patients? A Controlled Pilot Study



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