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Fibroids an excessive bleeding

by Anne
(Sweden)

I am a 43 year old woman who had a problem with fibroids and heavy bleeding. I've had the fibroids for many years but no symptoms. The bleeding started 6 month ago and is really heavy and lasted firtst for 30 days, then it didn't bleed for 2 months, then it started again and I bled for almost 50 days.

I really eat well, exercise and meditate and am healthy and fit, but this bleeding... After 50 days of constant bleeding I started to eat Primolut-Nor which is a synthetic progestene and it made me stop immediately. I don't like to take synthetic stuff but that was really a relief. My hb was down in 75. My estradiol is 926 pmol/L and my progesterone is less than 3 nmol/L. My thyroid also showed signs of hypo (8.7 mIE/L).

I cannot discuss such a thing as estrogen dominance with Swedish doctors because here in Sweden that is not considered as something that exists as a diagnosis, i.e. not treatable.

Well, I want to ask you if you consider my progesterone low and if I could have estrogen dominance? I have been taking progesterone cream for a month and really try to live very healthily in every way and don´t really know what to do more to get my estrogen down (if this is necessary). I hope that you can help me in any way. Do you have any advice for me and do you have any suggestions about why I'm bleeding? How does it all fit together and what is the core issue? Bless you for trying to help women with theese kinds of problems.

Kind regards from Anne in Sweden

Comments for Fibroids an excessive bleeding

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Oct 27, 2009
 Fibroids and excessive bleeding
by: Wray

Hi Anne. Thanks for your kind words! Fibroids are stimulated by oestrogen and suppressed by progesterone. You might like to see this web page, it gives more information.

From about the age of 35 our progesterone level starts dropping. It would appear yours has reached a level where bleeding has become severe. Your oestrogen is very high compared to progesterone. I do agree about the synthetic, to my mind far to dangerous to take, we have another web page on this here.

Pity about the doctors, but few know about oestrogen dominance, which you certainly have. Progesterone will help, but the dose will have to be high, between 200-300mg/day. I've found in helping others low doses do not stop heavy bleeding. Fibroids, endometriosis too, are a sign of oxidative stress. Please consider taking 2000-3000mg/day N-acetyl cysteine, a potent antioxidant. I also suggest you have a vitamin D test done, and if low to supplement with that, about 5000IU's/day. Take care, Wray
Jun 02, 2012
 Excessive bleeding
by: Anne

Hello, i am 49years old and my period has since last year become irregular. I have also been diagnosed with fibroids both inside and outside the uterus. In April 2012 my period which usually lasts for 5 days, went on for close to 10days. But in less than three weeks after ceasing the bleeding resumed with blood clot without the usual menstrual cramps and continued unabated for over 21 days. I saw my Doctor who prescribed Primolut 15mg (3 5mg) per day for 20 days. Within two days of taking the Primolut, the bleeding stopped but i have continued as i was told that there was likelihood of withdrawal bleeding. I am rather concerned about taking the Tablets for the twenty days esp because of possible side effects but on the other hand, i am afraid that if i stopped after 10days, the bleeding would resume. Please advise.
Jun 04, 2012
 Excessive bleeding
by: Wray

Hi Anne It's unfortunate Contraceptives are used to stop bleeding. Primolut is a 19-Nortestosterone derivative, ie it's derived from testosterone so has some androgenic properties. There's more info on this page here.
(Scroll down to the second link on Google to see the full pdf article entitled "Classification and pharmacology of progestins"). Progesterone is excellent for heavy bleeding, safe too unlike the contraceptives. You might like to read this comment here. 400mg/day is needed to stop it, then the amount should be reduced slowly over a few weeks till the optimum is found. We do have more info on our Menstruation page. The amino acid NAC (N-acetyl cysteine) should be considered too, this inhibits the MMPs which cause the heavy bleeding. About 2000mg/day should be taken. There's info about the MMPs on the menstruation page. Vitamin K2 is another possible addition, this can be low if heavy bleeding is experienced. You are now in the end stages of Peri-menopause which is a very difficult time. Should you consider progesterone, cycles are too erratic to follow so I recommend using it daily. Progesterone does help Fibroids which are caused by oxidative stress. This needs to be reversed, large amounts of antioxidants are needed, very often it's a lack of vitamin D causing them, see here, here, here and here. Continued below.
Jun 04, 2012
 Excessive bleeding Part 2
by: Wray

Hi Anne Please have a vitamin D test done. For more info on vitamin D levels, test kits etc see the Vitamin D Council, GrassrootsHealth, Birmingham Hospital and Vitamin D Links websites. Blood levels should be 70-100ng/ml or 175-250nmol/L and not the 30ng/ml or 75nmol/L most labs and doctors regard as adequate. The minimum daily dose should be 5000iu's per day, although the latest research indicates it should be 10,000iu's per day, see here. Take care Wray

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