Menu

Can progesterone cream help me if I have Premature Ovarian Failure (POF)?

Hi Wray -

I've been diagnosed with POF - how likely is it that natural progesterone cream will induce a period? I would like to try and get pregnant, but with my diagnosis and age, I'm not feeling very hopeful.

In 2013, at age 39, I went off birth control pills after 18 years and had irregular periods (which I assumed was my body adjusting.) After going 4 months without a period, I went to an endocrinologist who ran lab tests with the following "post-menopausal" results:

FSH: 169
Estradiol = 32
AMH = < 0.03 (undetectable)

I was put on Provera for 10 days to induce a period which never came. 2 weeks later, I had an ultrasound done where 4 follicles at 8mm were found (2 on each side). The endocrinologist was surprised and told me I should expect a period soon. He also told me I have no cysts, no fibroids and my uterus looked very healthy.

My period did not come that month, so I began Chinese herbs and acupuncture. 2 months later (so a total of 7 months), I finally got my period and exactly 28 days later, I got another. I thought I was cured, but 8 months have passed again and no sign of a period.

Since then, I've been taking many supplements in addition to my herbs: multi-vitamin, CoQ10, ProOmega-D, Evening Primrose, Symplex F, Ovex and DHEA (25mg).

I also went to a compounding pharmacy to have saliva testing done. Results showed I was low in progesterone and DHEA. That's when I was prescribed natural progesterone cream to try and kickstart a period - however, it's been 2 months now with no luck.

I should mention that POF does not run in my family - my mom went through menopause at 55 and my sister is getting her period regularly at 47. I also tested negative for multiple antibodies tests, Fragile X, Turner's Syndrome, etc. Aside from amenorrhea and terrible numbers, I have no other POF or menopausal symptoms - i.e. no hot flashes, no night sweats, no vaginal dryness, no brain fog, no insomnia. I eat mostly all organic food, exercise regularly and am not overly stressed.

Your thoughts would be greatly appreciated. Thank you -


Comments for Can progesterone cream help me if I have Premature Ovarian Failure (POF)?

Click here to add your own comments

Dec 13, 2015
 the same
by: Anonymous

I´m very interested in the answer, because I´m in a very similar situation - after birth control pills no period in 38, after 6 month some bleeding after the treatment with herbs, NATPRO. I have very irregular period since then, I have had low progesterone and low oestrogen, but my LSH was O.K. I had tried NATPRO for half year every day 200mg, after that I lovered the amount to 130mg. I have tried to follow some cycle and was on for 21-or 14days and for 7-or 14days off, but nothing has changed. After 2years of this irregular period, now, I have also LSH worse, so I´m in perimenopause. It is very bad, because I have also strong osteoporosis and I have to take medicine for that. My vitD levels are O.K.I take D3, Ca, Mg, K2, Minerals, vit C, Fish oil.

Click here to add your own comments

Join in and write your own page! It's easy to do. How? Simply click here to return to Progesterone faq.

Share this page:
Find this page helpful? Please tell others. Here's how...

Would you prefer to share this page with others by linking to it?

  1. Click on the HTML link code below.
  2. Copy and paste it, adding a note of your own, into your blog, a Web page, forums, a blog comment, your Facebook account, or anywhere that someone would find this page valuable.

Search over 8,400 pages on this site...